Research On The Effects Of Quality Of Life In Patients With Advanced Lung Cancer By FUZHENGSANGJI Decoction And Chemotherapy

Research background:primary bronchial lung cancer (lung cancer), is one of malignant tumors harm to people's health and life, Includes two major categories of small cell lung cancer and non-small cell lung cancer which accounts for about 85%, In recent years, the influence of smoking and air pollution, The morbidity and mortality of lung cancer in the past one hundred years has a faster rate of climb,and has become the first incidence of malignant tumors, At present has become the common malignant tumor in the city's first, Nearly 80% patients with lung cancer lost the best time in clinic surgery or radical treatment, The median surial rates of patients with advanced lung cancer less than a year now, Only 15.8% lung cancer patients confirmed can survive for 5 years or more, Individualization of evidence-based medicine of traditional Chinese medicine health care shows its advantages in the treatment of lung cancer. In improving the clinical therapeutic effect of lung cancer, Effectively improve the quality of life of patients with lung cancer, Especially improve the life quality of patients with advanced lung cancer has an irreplaceable rolePurpose of research:Whether lower TCM clinical syndrome score and serum carcinoembryonic antigen (CEA) value, alleviate lesions, stable weight, improve the quality of life, KPS score changes in the two groups before and after treatment, and treatment of adverse reactions,to explore the diagnosis and treatment with FUZHENGSANGJI Decoction compared with western medicine chemotherapy in patients with advanced lung cancer.Research methods:60 cases in the group were randomly divided into Chinese medicine group and the chemotherapy group,30 cases each. Control group (chemotherapy) using predominantly polonium agent chemotherapy regimens,28 days repeat, evaluation of 28 days; TCM group taking the FUZHENGSANGJI Decoction, evaluation of a 2 weeks, Record the main syndrome was observed, carcinoma of body change, KPS score, weight change, carcinoembryonic antigen (CEA) and the change of adverse reactions.Research results:In the aspect of clinical syndrome integral and score to improve the situation, the traditional Chinese medicine and chemotherapy group syndrome to improve the efficiency of 76.67% and 50%respectively, there are differences between the two groups of efficient statistics (p<0.05), Karnofsky score difference before and after Chinese medicine treatment group compared with chemotherapy group had obvious rise, suggests that the FUZHENGSANGJI Decoction has a significant effect to improve the lives of patients with advanced lung cancer (p<0.05), The traditional Chinese medicine group after treatment than chemotherapy group weight to increase and stability significantly higher than that of western medicine chemotherapy group, the weight loss was significantly lower than chemotherapy group, statistical differences in the two groups (p<0.05).Explain the traditional Chinese medicine FUZHENGSANGJI Decoction in improving clinical syndrome in patients with lung cancer have obvious advantages. No cases of bone marrow inhibition and TCM group, western medicine chemotherapy group cases of slight bone marrow suppression, but no statistical differences two groups effect on bone marrow suppression. Objective control in tumor and the tumor index carcinoembryonic antigen (CEA) effects, Chinese medicine group and the difference before and after chemotherapy group, the comparison between groups, no statistically significant (P>0.05).Research conclusions:it can better improved that the patients with lung cancer related major clinical syndrome, the weight, and the quality of life, reduce adverse reactions by FUZHENGSANGJI Decoction compared with the pure chemotherapy, but objective in tumor control rates and lower serum carcinoembryonic antigen (CEA), its no advantage compared with chemotherapy.