| BackgroundHyperthyroidism refers to a group of clinical syndromes, which the main performance is owing to too much thyroid hormone produced by thyroid itself, Human body systems such as nerve, loop, and digestive have the increased excitability and hypermetabolism.The research data show that the probability of women suffering from the disease is significantly higher than male, especially in the gestation age of women. Basal metabolic rate in pregnancy women can raise. The interaction between hyperthyroidism and pregnancy can affect the body function of pregnancy period, which cause a series of complications, and all kinds of bad influence on pregnant women and fetus. Pregnancy with hyperthyroidism is a common complication during pregnancy,belonging to the high-risk pregnancy.It’s known that the pregnancy outcome is closely related to the severity of disease and the treatment effect.Clinical management of this situation is quite different from that required by non -pregnant hyperthyroid women and poses significant diagnostic and therapeutic challenges.Therefore,Pregnancy with hyperthyroidism in recent years, is more and more get the attention of scholars both at home and abroad.What’s more,the screening of thyroid disease in clinic are also more and more common.The purpose of this article is to discuss the effect of hyperthyroidism with pregnancy on the pregnant outcome and the evaluation of reasonable treatment in improving the pregnancy outcome and other related issues. ObjectiveThrough a retrospective comparison and analysis, to investigate the diagnosis, treatment and prognosis of pregnancy complicated with hyperthyroidism. Materials and MethodsFrom February 2011 to September 2015, 64 cases of pregnant women with hyperthyroidism in our hospital were retrospectively analyzed. 58 cases of normal pregnant women as the control group, and two groups of patients with disease control group were analyzed, and the third groups were observed. Results(1) Thyroid hormone levels: TSH, FT3, FT4 and control group(P < 0.05), there were significant differences in control group.(2)The maternal adverse outcomes: gestational hypertension, gestational diabetes, placental abruption, hyperthyroid heart disease, hyperthyroidism crisis, abortion, premature birth rate in control group was significantly lower than non pregnancy control group(P < 0.05), there was significant difference between the control group and the control group showed no significant difference.(3) The comparison of perinatal adverse outcomes: fetal distress, fetal intrauterine growth restriction(IUGR), neonatal asphyxia, fetal death rate of control group was significantly lower than non pregnancy control group(P < 0.05), there are significant differences of the above analysis of specific data, statistical differences in study but also the development of the control group did not appear also, no statistical difference in control group the same phenomenon. ConclusionThe pregnant women with hyperthyroidism can only choose the appropriate time to conception, early diagnosis, active treatment, and closely monitor the situation of maternal and neonatal. |
