| Purpose: Using Functional magnetic resonance T1.T2 FLAIR 3D structure sequence and ALFF analysis of resting state functional magnetic resonance to make a systematic research on cognitive and neural mechanisms of motor aphasia caused by craniocerebral trauma and hemorrhage stroke.And to explore the evaluation index of the prognosis on the fMRI.For the majority of neurosurgeons providing the image evidencein whether the recovery when they are asked by the patient family members,better and more efficient to evaluate the prognosis of patients,and guide the late rehabilitation treatment,to improve the level of diagnosis and treatment.Method: Functional magnetic resonance examination was performed on 20 patients with motor aphasia caused by craniocerebral trauma and hemorrhagic stroke(including acute subdural hematoma in 5 people,11 people left basal ganglia hemorrhage,arteriovenous malformation 4)in Department of Neurosurgery,Affiliated Hospital of Hangzhou Normal University from December 2014 to 2015,making following sequence check on 3.0TfMRI: 1.resting-state functional magnetic resonance imaging,RS-fMRI;The sampling time is 8 minutes,In before the start of the scan,told patients to relax mood,relieve stress,even breathing,never nervous,cranky,give patient safety alerts remote control,so that patients in the meet an emergency can inform.In the scan,the magnetic resonance indoor lights off,to avoid interference.Do the low-frequency amplitude on resting state fMRI data(amplitude of low frequency the fluctuation,ALFF analysis);The collected data were pretreated in resting state,mainly includes the following steps:(1)Remove the 10 resting state fMRI images before the time point data(2)Slice Timing;(3)Head Motion Realign(4)Spatial Normalization(5)Smooth(6)Remove Linear Tread(7)Filtering(8)Go to the covariate.2.spoiled gradient recalled echo T1-weighted imaging,SPGR-T1 WI;The scanning time is 5 minutes and 5 seconds,mainly used to observe the structure and production of whole brain gray matter template using 3D-T1 image acquisition,acquisition of whole brain low-frequency amplitude diagram.3.fluidattenuated inversion recovery,FLAIR,It is mainly used for better observation like structure.After 3 months follow-up,including patients with aphasia recovery and magnetic resonance measurement results,to explore the significance of functional magnetic resonance imaging to guide their prognosis.Result: In 20 cases of traumatic brain injury and Anandia hemorrhagic stroke were collected for this study,the ALFF analysis indicated that language function abnormal brain activity,Further confirmed the cause of motor aphasia caused by the left posterior inferior frontal gyrus and adjacent areas of the lesion.At the same time,we found that not only the left inferior frontal gyrus,and posterior brain areas in abnormal and intracranial multiple brain regions appear different degree of increased and decreased.16 cases of patients with poor prognosis in the study,but were improved,aphasia legacy to a certain extent.Comparison of aphasia recovery of patients with good and poor recovery of patients,we found,patients with good recovery,followed by buckle back to district Alff values decreased extent less than poor recovery of patients,the right side of the image area(mirror region appear with different degrees of active enhancement.Conclusion: Using functional magnetic resonance imaging technology,combined with 3D T1.T2 FLAIR sequence structure and resting state functional magnetic resonance Alff analysis,from a certain degree to evaluate the prognosis of motor aphasia.The cingulate regions of the brain ALFF value and the right image area is increased have a close relationship with the prognosis of the patients. |
PDF Full Text Request