| BackgroundBrugada syndrome refers to a disorder characterized by sudden death associated with one of several ECG patterns characterized by incomplete right bundle-branch block and ST-segment elevations in the anterior precordial leads,which is caused by genetic factors.Brugada syndrome is an autosomal dominant inheritance?incomplete penetrance?.in 1917,Brugada syndrome was firstly reported from the Philippine medical journal in the world.in 1986,Spanish scholars Pedro Brugada and Josep Brugada discovered that 3 year old boy in poland was sudden death after a recurring syncope,unanswered heart plane change,electrocardiogram?ECG?tipping right bundle branch block,chest leads V1 and V3 visible ST-segment elavation,ECG prompting ventricular fibrillation occurs during the syncope.In 1992,Pedro Brugada and Josep Brugada summary reported 8 cases of idiopathic polymorphic ventricular tachycardia and idiopathic ventricular fibrillation,which electrocardiogram?ECG?showing the right chest lead ST segment continues to raise with or without the right bundle branch block?RBBB?,while there is no anatomical change in cardiac of patients.This finding attracted the attention of worldwide.after that,similar cases reported increased gradually.In 1996,the Japanese scholar Miyazaki Pedro named the sustainability of ST segment elevation and sudden death disease report as Brugada syndrome.in 1998,Brugada syndrome was firstly reported in China by a Chinese,Xiong Kaining.According to epidemiological data,Brugada syndrome is mainly distributed in Asia,the incidence of southeast Asian nations as much as l %,Therefore,Brugada syndrome is called as “Southeast sudden unexplained nocturnal death syndrome.ObjectiveStudy and understand the etiology,diagnosis and treatment of Brugada syndrome.ResultsAccording to references and case analysis concluding that: For the patients in children which first time attacked after eating "raspberry" drinks,before appearing chest pain again as well as had ate 'raspberry nuts' therefore,in this case may exist a reason that after the patient had eating the raspberrie,an unknown ingredient in Raspberries leads a Brugada wave-like change in ECG of children.2.There is a presented report that fever can lead to Brugada wave change,the temperature of the patient body is 38.0 ?,ECG wave-like changes may relate to heat.3.The relevant tests: blood routine: white blood cells: 23 × 109 / L;Neutral cell rate: 76.01%;Lymphatic rate: 21.5%;Hemoglobin: 121 g/l;Platelet: 351.0 × 109 / L.Amylase: 60 u/L.Lipase: 50 u/L.There were no abnormal in liver function and electrolyte.CRP: 0.01 mg/L.Myocardial enzymes,troponin and amylase in the normal range.Imaging examination: liver,gallbladder,pancreas and spleen.b-ultrasound examination: b-ultrasound tips the ultrasonographic of liver,gallbladder,pancreas and spleen not seen obvious abnormity,the right lower abdomen appendix not seen obvious abnormity.No obvious abnormal in heart echocardiography.Electrocardiogram?ECG?prompts sinus rhythm 119 times/min,Brugada wave change.?figure 1?X-ray suggests the weight of both lungs texture.Reexamination of electrocardiogram?ECG?tip: sinus rhythm,T-wave change.Reexamination of myocardial enzymes and blood inflammatory indicators.Routine blood: white blood cells: 15.33 × 109 / L;Neutral cell rate: 67%;Lymphatic rate: 28.6%;Neutral cell number: 10.27 × 109 / L;Lymphocyte count: 4.39 × 109 / L;Hemoglobin: 123 g/l;Platelet: 293.0 × 109 / L.PCT: 1.36 ng/L.CRP: 20.94 mg/L.Troponin-i < 0.001 ng/ml.Heart colour to exceed tip: mitral valve and tricuspid valve and pulmonary valve regurgitation?mild?,no seen the left heart function unusual,arrhythmia,left ventricular false chordae tendineae.the 7th day of treatment in children with clinical signs,no abnormal electrocardiogram?ECG?.ConclusionAccording to summarizes relevant literature,combined with the case at the same time,the cause of Brugada syndrome factor have the gene theory,some physical factors or other factors are not found by now.Whereas,there are some suggestions for the clinical diagnosis,treatment and prevention of Brugada syndrome.while with the improvement of the scientific research level is likely to have further study on Brugada syndrome. |
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