Research The Effect Of Osteoporosis On Bone Fusion After Posterior Lumbar Interbody Fusion

Objective: To investigate the influence of osteoporosis about bone fusion after posterior lumbar interbody fusion(PLIF).Methods: 62 patients(degenerative lumbar instability syndrome)treated by PLIF were divided into 2 groups according to the preoperative bone mineral density:28 cases were split into group A(the osteoporosis group),while the other 34 cases(the normal bone mass group)were distributed into group B.The VAS scores,the JOA scores and the Nakai scores were both used to evaluate the clinical effect,and the method which was recommended by the U.S.Food and Drug Administration was used to estimate the final fusion conditions of these patients.Results: Compared with the fusion rate,the fusion time,the final VAS scores,the final JOA scores,the Nakai result were all statistically significant difference(P<0.05)between 2 groups,and compared the final VAS scores or the final JOA scores to the preoperative VAS scores or the preoperative JOA scores were also both statistically significant difference(P<0.05)within each group.Conclusion: PLIF is a reliable method for the treatment of the degenerative lumbar instability syndrome,but osteoporosis may reduce the fusion rate and the clinical effect,prolong the fusion time and even lead to fusion failure by accelerating graft-bone absorption,restraining the formation of new bone,inducing the implant instability.