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Analysis Of The Short-term Effects Of The Treatment On Knee Osteoarthritis By Extracorporeal Shock Wave

Posted on:2017-01-27Degree:MasterType:Thesis
Country:ChinaCandidate:L ZhengFull Text:PDF
GTID:2334330485476299Subject:Surgery
Abstract/Summary:PDF Full Text Request
Objective: To comparatively investigate the clinical efficacy between extracorporeal shockwave and oral nonsteroidal anti-inflammatory drug in the treatment of knee osteoarthritis.Methods:Patients admitted from October 2015 to March 2016 and screened according to the clinical inclusion and exclusion criteria were randomly divided into ESWT treatment group and observation group applying nonsteroidal anti-inflammatory drug;a standardized treatment was performed in strict accordance with related courses.WOMAC scoring and VAS pain scoring were conducted in all patients before treatment.The divergent impact therapy was used(in the ESWT treatment group)and certain courses of regular ESWT treatment were performed in the patients by reference to the energy parameters set by Wu Wei [1](set the frequency of treatment to 20.0Hz and bend the affected knee to 90°;first exert 1000 shocks to the pain point,and then exert 2000 shocks to the surrounding soft tissue around the pain point in a slow and reciprocating manner,thus generating a total of 3,000 shocks;based on patient tolerance,start the shockwave energy from 1.5bar and gradually increase it to patient's maximum tolerated energy,which is generally set at 2.0-4.0bar;conduct ESWT treatment once a week for 4 successive weeks).For patients in the oral administration group,200 mg nonsteroidal anti-inflammatory drug(celecoxib)was orally administrated once a day for 4 successive weeks.WOMAC scoring and pain scoring were performed again immediately after the treatment courses and at one month later to assess the treatment efficacy of shockwave and oral administration.The data was collected and statistically analyzed.SPSS22.0 software was used for statistical analysis,where the results of measurement data were represented by the mean ± standard deviation,and paired t test was used for statistical test.P<0.05 was defined as a statistically significant difference.Results: In patients treated with strict and regular extracorporeal shockwave and those treated with oral nonsteroidal anti-inflammatory drug,WOMAC and VAS scores immediately after the treatment courses and at one month later were lower than those before treatment in both groups;both the WOMAC and VAS scores of the shockwave treatment group were lower than those of the control group at one month after the treatment courses(P <0.05),suggesting a statistically significant difference.Furthermore,the side effects appeared to be fewer.Conclusion: Compared with nonsteroidal anti-inflammatory drug,extracorporeal shockwave is featured by better efficacy and lower side effects in the treatment of osteoarthritis.
Keywords/Search Tags:Extracorporeal shockwave, Knee osteoarthritis, Nonsteroidal anti-inflammatory drug
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