The Investigation Of Primary Liver Cancer Risk Factors And The Correlative Research Of Syndrome Type And Physicochemical Indexes

Objective: To investigate the related risk factors for primary liver cancer incidence, and provide reference basis for prevention of liver cancer. We analysed clinical characteristics of 90 cases of patients with primary liver cancerand discuss TCM syndrome type and the relationship between the liver function, blood coagulation indexes, blood routine test,and to provide experimental basis for the research of TCM syndrome typing.Methods: We made an epidemiological analysis of 90 cases of PLC patients and related risk factor of liver cancer,and divided them into four types: qi and blood stasis type,hot and humid type,stagnation of liver qi and spleen deficiency type, liver and kidney Yin deficiency type, and compared the syndromes by liver function, blood coagulation indexes, blood cell analysis,to discuss the relevance. Make the ststistics with the SPSS17.0 statistical software,and use the the chi-square test for the enumeration data, and rank sum test for the measurement data, make P < 0.05 as a test level.Results: 90 cases of primary liver cancer patients are predominantly male, male to female ratio is 3.5:1. Mean age 58.77 ± 9.82 years old, mainly concentrated in 50 to 59 ages. In patients with liver cancer, 72 cases of patients with HBV, 58 cases of cirrhosis, HBV liver cancer patients not taking antiviral drugs and discontinuous taking medication,the incidence of liver cancer is significantly higher than early take antiviral drugs in patients with HBV.In all the patients,drinking patients accounted for 54.4%, smoking patients 51.1%, poor quality of sleep of the patients(58%),unhealthy diet patients 54%. TCM syndrome type survey found that early HCC is given priority to with qi and blood stasis, hot and humid alternating knot, middle-late with liver-kidney Yin deficiency, mainly to stagnation of liver qi with deficiency. There was no significant difference between each type and liver function(P > 0.05), but in each ttpe the value of ALT and AST both increased; And between them the coagulation index had significant difference(P < 0.05), liver and kidney Yin deficiency type is more easy to bleed; There was no significant difference in AFP value.(P > 0.05).Conclusion:50 to 59 yeares old, male, HBV, liver cirrhosis, drinking, smoking, bad character,and serious lack of sleep are risk factors for primary liver cancer;There are certain relations between types and coagulation indexes, liver function, AFP.