Efficacy Observation Of Qingyitang Combined With Early Enteral Nutrition For Treatment Of Mild Acute Pancreatitis

Objective:Enteral nutrition and the combination of traditional Chinese andwestern medicine are currently usually applied in the treatment of severe acutepancreatitis, with remarkable effects and dramatic decrease of mortality rate.Clinically the mild acute pancreatitis is the most common, taking up80%of themorbidity of acute pancreatitis, compared with the acute necrotic pancreatitis, itscondition of the illness is relatively lighter and it can be cured with regular treatment,but its course of disease is longer and its medical fees higher,with occasionallyrecurrent attacks, it is possible to convert into severe acute pancreatitis. This thesisapplies the principle and method of statistics to compare the difference of curativeeffects between the treatment of Qingyitang and conventional western remedycombined with early enteral nutrition and the treatment of conventional westernremedy for mild acute pancreatitis, providing clinical reference for a morereasonable, more economic and more effective scheme for the choice of clinicaltreatment of mild acute pancreatitis.Methods:Collect60cases of the patients of mild acute pancreatitisreceived and cured by our department from April2012to December2013allthe patients conforming to the diagnostic code of acute pancreatitis, andeliminate the patients with serious complications through correspondingexaminations. Among them, there are41male cases and19female caseswith the age from22to75years old and the average age of48.5years old.There are29cases of gallstone pancreatitis,16cases of insobriety andengorgement and15cases of other reasons. These patients are divided intotreatment group (30cases) and control group (30cases) according to randomallocation principle. The control group receives conventional westerntreatment (including fasting and water deprivation, effective gastrointestinaldecompression, acid suppression and suppression of pancreas, anti-infection,analgesia, maintaining water and electrolyte balance, and total parenteralnutrition therapy). The treatment group is given additional Qingyitang combined with enteral nutrition treatment24h after admission on the basis ofconventional western treatment. Compare the recovery time of abdominalpains and distension between the two groups, the recovery time of abdominalCT, the recovery time of blood amylase, serum lipase, urine amylase andC-reactive protein, the duration complete fasting, the average length of stayand hospital costs, the conditions of nutrition changes of patients after thetreatment (serum albumin).Results: Compared with the control group, the recovery time of abdominaldistension and pains, the duration of fasting and the average length of stay areremarkably shorter in the treatment group; the hospital costs are less too, the overtdifference of comparison is statistically significant (P<0.05). The recovery time ofblood amylase, serum lipase and urine amylase in the treatment group are shorterthan those in the control group, the recovery time of abdominal CT and CRP are alsodistinctly shorter than those in the control group, the remarkable difference ofcomparison is statistically significant (P<0.05).Conclusion:Qingyitang can prevent the gastrointestinal mucosa from furtherdamage, rapidly promote the recovery of each function of the gastrointestinal tract,alleviate the damage of pancreas and peri-pancreatic tissues, promote theself-recovery of pancreas, decrease the overproduction of C-reactive protein, so as toease the acute inflammatory reaction and shorten the course of disease. Enteralnutrition can improve patients'nutritional conditions,prevent the intestinal tract fromdisuse-atrophy, decrease the complications caused intestinal bacterial translocation,improve patients' prognosis and reduce hospital costs.