Sleep Quality And Sleep-related Breathing Disorder Of Patients With High Altitude Polycythemia Arrived At Moderate Altitudes

Objective: To investigate the nighttime sleep quality, sleep-related breathing disorderand blood oxygen saturation characteristics of patients with high altitudepolycythemia arrived at moderate altitude area, and provide a theoretical basis for themechanism and clinical prevention of high altitude polycythemia.Method:12cases patients with high altitude polycythemia and healthy people wereselected respectively, the polysomnography, observed total sleep time (TST), sleepefficiency (SE), non-rapid eye movement sleep (N-REM), rapid eye movement sleep(REM), apnea-hypopnea index (AHI), the average oxygen saturation (MSaO2), thelowest oxygen saturation (LSaO2), the average magnitude of desaturation (MODD),oxygen desaturation index (ODI) and other relevant indicators were detected.Results: There are no significant differences of TST, SE, N-REM, REM betweenpatients with high altitude polycythemia and healthy people. Compared with healthypeople, the AHI, MSaO2, LSa02, MODD, ODI have obviously differences in patientswith high altitude polycythemia. LSaO2of patients with high altitude polycythemiaare negatively correlated with AHI, and MODD, ODI of patients with high altitudepolycythemia are positively correlated with AHI.Conclusion: There is no significant difference of sleep quality between patients withhigh altitude polycythemia and healthy people, the increaseing of AHI can lead to thereduction of SaO2.