| ObjectiveOur country is a high-incidence area of gastrointestinal cancer,early detection,early diagnosis and early treatment can significantly improve the survival rate of patients and improve the prognosis and quality of life.Chromoendoscopy is an important method for the diagnosis of early gastrointestinal cancer and can effectively improve the detection rate of the disease.The existing endoscopic gastrointestinal mucosal staining method is to manually configure the dye,and dye the syringe by hand to push the syringe.This process is cumbersome,time-consuming and labor-consuming,and the work efficiency is low.In order to solve the above problems,this study intends to develop a multi-channel intelligent staining pump,so as to optimize the existing endoscopic gastrointestinal mucosal staining,cleaning,water injection and other liquid feeding operations,to provide a new type of equipment for improving the efficiency of medical staff,and exploring a new method to improve the detection of early cancer of the digestive tract.Methods1.According to the principles of smart,efficient,versatile,and easy to use,the design of multi-channel intelligent staining pump includes intelligent control part,liquid driving part,liquid passage part and other fitting parts.The intelligent control part accurately distributes the liquid flow rate and working time.The liquid driving part draws the required reagents to the endoscope.The liquid passage completes the liquid conveying operation.Other accessories canimprove the convenience of operation for liquid feeding under the endoscope.2.According to the actual needs of clinical work,multi-channel intelligent staining pump component selection and parameter setting.According to the principles of program editable,large memory capacity and small chip size,the general-purpose single-chip microcomputer is selected as the core component of intelligent control,and various parameters related to the liquid-feeding operation under the endoscope can be written and programmed;the display is clear and the operation is simple.The principle of choosing the touch-sensitive LCD screen as the operation panel can display the various functions of the multi-channel intelligent staining pump on the screen intuitively,which is convenient for the operator to set and use in the operation;combined with the existing endoscopic liquid feeding operation.The amount of liquid,and based on the principle of adjustable flow rate,stable operation,safety and reliability,the peristaltic pump driven by a stepper motor is selected as a liquid driving device,and the liquid flow provided by the peristaltic pump can meet the use requirements of various endoscopic liquid feeding operations;According to the existing endoscopic mucosal staining,washing,administration and other operations of the reagent dosage selection of suitable size of the reservoir bottle as a reagent storage device;according to the principles of corrosion resistance,anti-oxidation,high elasticity and other medical grade silicone tube used as a pump tube,And according to the actual liquid demand and peristaltic pump model to select the pump tube specifications;to achieve multi-channel intelligent dye pump multi-function Sexuality,design layout of multiple liquid passages,use custom multi-pass connections to integrate the various passages;customize accessory components such as air pump,spray tube,flush tube,pedal,remote control,battery,etc.according to operating requirements in the liquid feeding operation.3.According to the principle of small portable,easy to operate,reliable anddurable design,the various components of the multi-channel intelligent staining pump are assembled as a whole.According to the principles of lightweight and easy processing,aluminum alloy is used to make the shell of the complete machine;according to the maximum space utilization,the SCM is built into the control panel and placed on the top of the host through the slide rail;based on dust,water,and electromagnetic interference The principle is to install the peristaltic pump,air pump,and power supply inside the host;to facilitate the observation and replacement of the reagent,place the liquid storage bottle outside the host;and use a multi-pass connection to converge the various liquid passages at the liquid outlet terminal.4.Functional Verification and Optimization Improvement of Multi-channel Intelligent Staining Pump: Observe the spraying status of multi-channel intelligent staining pump,measure the spraying scope,verify the feasibility of the dyeing operation for endoscopic mucosal membranes,and measure the feasibility of each peristaltic pump with the weighing method.The liquid flow range is compared with the existing endoscope pump to verify the feasibility of water injection for endoscopy;a multi-channel smart dye pump is used to flush the intestinal mucosa,and the intestinal cleanliness before and after washing is recorded.Compared with the existing intestinal mucosal irrigation method,the feasibility of the endoscopic irrigation procedure was verified.Through summarizing and analyzing the defects and deficiencies in the functional test,the multi-channel smart staining pump was optimized and improved,and the performance test was performed again to verify the feasibility of applying liquid feeding under the endoscope.5.The application of multi-channel intelligent staining pump in esophageal iodine staining: Select 110 patients with suspicious lesions in esophageal tube from gastroscopic examination at the Digestive Endoscopy Center of the General Hospital of Armed Police Forces from June to December 2017 andexclude 110 patients with contraindications.For the experimental group and the control group,55 cases in each group.The experimental group used a multi-channel intelligent staining pump to perform iodine staining on the esophagus,and the control group used a syringe to perform iodine staining on the esophagus.The numbers,time,reagent dosage,lesion detection rate,and medical satisfaction degree of the two groups were recorded.Statistical analysis was performed on the collected data to compare the differences between the two groups and to explore the application value of the multi-channel staining pump in esophageal iodine staining.Results1.Multi-channel intelligent staining pump consists of four parts,namely intelligent control part,liquid drive part,liquid transport part and other parts of accessories.The main components include peristaltic pump,air pump,single-chip microcomputer,operation panel,liquid bottle,pump tube,multi-pass Connections,power supplies,spray tubes,pedals,etc.2.The single-chip microcomputer selected by the multi-channel intelligent staining pump is a general-purpose type,which is smaller than other intelligent chips and has a large memory and can be repeatedly programmed.The touch panel selected in the operation panel has the advantages of low energy consumption,high definition,and simple operation.The intelligent control part selects and sets the intelligent program written in the microcontroller through the operation panel,so that the liquid flow,flow rate,and working time can be precisely controlled,and various functions such as channel switching and pipeline flushing can be realized.The peristaltic pump with a flow rate of0-800ml/min was selected as the liquid infusion device according to the actual endoscopic staining operation.The peristaltic pump was driven by a stepper motor.Compared with the DC motor,it has the advantages of stable performance,safety and reliability,and adjustable output.Can meet the needsof a variety of endoscopic liquid feeding operations.According to the existing endoscopic staining,washing,and drug delivery operations,250 ml and 800 ml reservoir bottles were selected as the reagent storage device.Due to the corrosive and oxidative effects of some reagents used in liquid feeding under endoscopy,medical-grade silicone tubes with strong corrosion resistance and oxidation resistance were selected.The actual diameter of the endoscopes used for dyeing operations was selected as the diameter of the tube.2x4 mm and 4x6 mm pump tubes.Multi-pass connection made of acrylic material,small size,easy connection.In addition,the one-way valve in the liquid passage can effectively prevent the liquid from flowing back,and the Luer connector can connect the liquid passage to the spray tube.3.The size of the multi-channel intelligent staining pump is 50 cm x 25 cm x15cm,and the weight of bare metal is about 6kg.The internal components of the host are arranged in a compact and rational layout.The enclosure of the chassis can effectively play a role of dustproof,waterproof,and electromagnetic interference.The storage bottle is placed on the outside of the host so that the medical personnel can observe the dose and type of the reagent in the bottle at any time so as to add or replace it in time.The pump tubes in the plurality of liquid passages pass through the central portion of the main body upwardly into the operation panel and are converged into one through a multi-way connection,and the terminal can be connected to the endoscopic biopsy hole to transport the liquid into the digestive tract.4.Through the performance test,it is found that the principle of multi-channel smart staining pump assembled for the first time has the following problems: the number of access paths is small,the stability of the touch screen is normal,there is liquid residue in the pipeline,and the pump tube is easily corroded by reagents.The above-mentioned defects and deficiencies were optimized for the multi-channel intelligent staining pump.The mainimprovements were: increased the number and flow rate of peristaltic pumps,which can meet the needs of more liquid feeding operations under the endoscope;and changing the touch screen to mechanical buttons Improve the reliability of the equipment;Equipped with an air pump to reduce the liquid residue in the pipeline;Imported medical-grade silicone tube lined with Teflon coating can improve the anti-oxidation and anti-corrosion of the pump tube.Service life.The performance test of the optimized and improved multi-channel intelligent staining pump was performed again.The results showed that the multi-channel intelligent staining pump provided the liquid flow rate of 0-800ml/min.The spraying range changed with the flow rate,and the timing could be achieved through an intelligent control program.Quantitative feeding,path switching,pipeline cleaning and other functions can meet the needs of various liquid feeding operations under the endoscope,and the performance is superior to the existing endoscope water pump.The results of the application of multi-channel intelligent staining pump in intestinal mucosal irrigation showed that: the rinse time of the experimental group was 18.01±2.78 s,and that of the control group was 32.96±1.78 s.The t value of the two groups was 10.19,p<0.05.The difference was statistically significant;the water consumption of the experimental group was 56.82±8.91 ml,and the water consumption of the control group was 78.85±15.16 ml.The t value of the two groups was 68.30,p<0.05,and the difference was statistically significant;the mucosal washing of the experimental group was significant.The post-cleanliness score was 2.79±0.91.In the control group,the intestinal cleaning score after the mucosa was washed was 2.30±1.11.The t value of the two groups was 3.043,p<0.05,and the difference was statistically significant.5.The application of multi-channel intelligent staining pump in esophageal iodine staining showed that when a multi-channel intelligent staining pump was used for endoscopic esophageal iodine staining,the process from parametersetting to dyeing operation could be completed by endoscopic surgery.Then the assistants cooperated with the operation to reduce the waste of human resources.The duration of esophageal iodine staining in the experimental group was 15.47±2.72 s,and the esophageal iodine staining time in the control group was 28.17±2.29 s,and the t value was 28.245,p<0.05.The difference between the two groups was statistically significant;the amount of reagent in the experimental group was used.It was 15.84±2.71 ml.The amount of reagent in the control group was 18.73±2.20 ml,and the t value was 6.140,p<0.05.The difference between the two groups was statistically significant.The lesion detection rate in the experimental group was 38.00%.The lesions in the control group were examined.The rate was 26.00% and the x2 value was 1.905,p>0.05.There was no statistical difference between the two groups.The questionnaire showed that the satisfaction of the medical treatment in the experimental group was 90.00%,and the satisfaction of the control group was 58.00%.The x2 value was 6.140,p<0.05,there was a statistical difference between the two groups.Conclusion1.Successfully developed a multi-channel intelligent staining pump that integrates mucosal dyeing,rinsing,water injection,inflating,and drug delivery functions to realize precise control of liquid flow,operation time,channel switching,and tubing cleaning.Can meet the needs of a variety of endoscopic liquid feeding operations.2.The multi-channel intelligent staining pump is safe,reliable,and simple in operation.It reduces the number of operations,the time,and the amount of reagents used for the liquid feeding operation under the endoscope,thereby improving the work efficiency of the medical staff and reducing the work intensity.3.The multi-channel intelligent staining pump has good flushing and dyeing effects on the digestive tract mucosa,improves the detection rate of lesions,and is highly recognized by medical personnel.It provides a new type of equipment for improving the detection rate of early gastrointestinal cancer. |
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