Development And Application Of Novel Ion Imprinted Electrochemical Sensor

Ion imprinting technology as an important branch of molecular imprinting technique,the ion imprinting polymer was prepared for separation using ion as template,after chelated,by electrostatic and coordination function combined ion,the ion was washed after prepared spatial structure and binding sites of cavity structure of imprinted materials.Ion imprinted polymer has high selectivity,anti-interference ability,as the basis for the construction separation and detection.However,it is difficult to satisfy the requirements of trace analysis by electrode detection.In this paper,the modified the nano-material and ion imprinted polymer can increase sensitivity and selectivity of ion imprinted electrochemical sensor.The prepared of graphene,multi-walled carbon nanotubes,3D graphene oxide and C60 composite as modification material,using various methods modified surface of carbon electrode,developed ion imprinting electrochemical sensor for detection of Pb(Ⅱ),Cu(Ⅱ)and Cd(Ⅱ)was investigated.The research of contents was as follow.1.A novel copper ion imprinted sensor was prepared for sensitive and selective determination of copper with graphene as the modification material,copper ion as the template ion,and dopamine as the functional monomer.The ion imprinted electrochemical sensor was characterized by differential pulse voltammetry and cyclic voltammetry.The results showed that the imprinted sensor exhibits high sensitivity and selectivity toward copper ion.Under the optimized conditions,in the range of 5.0×10-6~5.0×10-11 mol/L,a good linear relationship was existed between the response current of the imprinted sensor and the negative logarithm of copper ion concentration with the detection limit of 1.0×10-11 mol/L.The ion imprinted electrochemical sensor was successfully used for the detection of trace copper ion in sample water.2.A universal and reproducible of double ions imprinted electrochemical sensor was prepared for simultaneous and sensitive determination of Pb(Ⅱ)and Cd(Ⅱ)with functionalized carbon nanotube as the sensitized material,Pb(Ⅱ)and Cd(Ⅱ)as double template ions,and L-histidine and trimethoxysilyl propyldiethylenetriamine as bifunctional monomers.The electrochemical performance of the double ions imprinted sensor was investigated with cyclic voltammetry and differential pulse voltammetry method in detail.The results showed that the double ions imprinted sensor exhibited high sensitivity and selectivity toward Pb(Ⅱ)and Cd(Ⅱ).Under the optimized condition,a linear relationship was existed between the response currents of the double ions imprinted sensor and the negative logarithm of Pb(Ⅱ)and Cd(Ⅱ)concentrations with the detection limit of 1.5×10-11 mol/L and 3.0×10-11 mol/L for Pb(Ⅱ)and Cd(Ⅱ),respectively.The double ions imprinted sensor was successfully used for simultaneous detection of trace level Pb(Ⅱ)and Cd(Ⅱ)in real sample.3.A novel multiple ion imprinted sensor was prepared based on 3D GO-C60 composite for simultaneous and selective determination of Pb(Ⅱ),Cu(Ⅱ)and Cd(Ⅱ)with methacrylic acid and edetic acid as functional monomer,Pb(Ⅱ),Cu(Ⅱ)and Cd(Ⅱ)as template ion.The performance of ion rinted sensor was investigated using cyclic voltammetry(CV),differential pulse voltammetry(DPV)and electrochemical impedance spectroscopy(EIS)in detail.Under the optimized conditions,a linear relationship was existed between the response currents of the ions imprinted sensor and the negative logarithm of Pb(Ⅱ),Cu(Ⅱ),Cd(Ⅱ)concentrations for Pb(Ⅱ),Cu(Ⅱ)and Cd(Ⅱ),respectively.The ions imprinted sensor was successfully used for simultaneous detection of trace level Pb(Ⅱ)and Cd(Ⅱ)in soil and plant sample.