Synthesis And Potential Applications Of Organic/Inorganic Hybrid Materials Under The Control Of Organic Molecules

Biomimetic mineralization is a powerful method,which is a common technique for the synthesis of materials with complex shapes,hierarchical structure and controllable size.Increasing the understanding of the mechanism of biological mineralization can greatly improve the feasibility of the method of biomimetic mineralization.Materials,such as nanoparticles,thin films and porous materials,which are produced by this new technology,often have special physical and chemical properties.The establishment of biomimetic synthesis methods of high performance inorganic materials has played an important role in the field of materials chemistry.Organic-inorganic hybrid materials due to its both the physical and chemical properties of organic molecular and inorganic molecules,often used as optical materials,electrical materials,biological materials,catalytic materials,chemical sensors,etc.With people for the further research of hybrid materials and their new features of development,it as a kind of excellent performance of new materials,will play a powerful role.This paper mainly carried on the following several aspects :Using different biological molecular including chondroitin sulfate(CS),sodium hyaluronate(HA)and surface active agent cetyl trimethyl ammonium bromide(CTAB),sodium dodecyl sulfate(SDS)as organic matrices,we synthesized a peanut-shape and ellipsoid shaped calcium carbonate,flower-like PbS nanoparticle,PbS quantum dots and ZnS nanospheres.Through a variety of testing methods,the surface morphology,microstructure and properties of samples were characterized.The results show that the morphology of the hierarchical hybrid materials is uniform and the particle size distribution is uniform.What’s more,ellipsoid shaped calcium carbonate has a porous structure,which can effectively load anti tumor drugs.Spherical calcium carbonate as a drug carrier and the doxorubicin hydrochloride(DOX-HCl)as a model of anti-tumor drugs,we have designed the drug adsorption and release experiment.The results showed that the DOX load rate reached 94.03% and the release results showed that carrier materials exhibit good pH sensitivity.Furthermore,the DOX could be released stability and sustainably from the carrier in acidic condition.These results provide a reliable basis for cell viability assay.Using human hepatocellular carcinoma cells(HepG2),mouse ascites tumor cells(S-180)and rat normal liver cells(BRL-3A)as models of tumor cells and normal cells,the antitumor activities of the the CS-CaCO3-DOX,flower shaped PBS and PbS quantum dots hybrid materials were studied.MTT assay results showed that the DOX can be ffectively inhibit the proliferation of tumor cells using the CS-CaCO3 carrier;Flower-like HA-Pb S and CS-PbS quantum dots have obvious inhibitory effect on the proliferation of the two kinds of cancer cells,but no significant inhibitory effect on normal cells.These results provide an experimental basis for the synthesis of hybrid materials in the field of tumor therapy.Using Rhodamine B(RhB)and Methylene blue(MB)as an organic pollutant model,we have studied the potential application of the synthesis of zinc sulfide nanoparticles in photocatalytic degradation.A large number of experiments show that the photocatalytic degradation of organic pollutants can be effectively degraded under the irradiation of visible light,and the photocatalytic effect is obvious,and can be recycled.The experimental results show that the degradation of the dye is related to the hydroxyl radical of the light.These results indicate that the synthesized nano spheres as photocatalyst has strong practicability.