The Dynamical Analysis Of Neuron Bursting And The Associated Simulation Of Optical Phase Characteristics Of Neuron

Neuron is the basic unit of the biological nervous system structure and function.It can encode,transmit and integrate the information by the discharge activities.The discharge activities involve complex process of physical and chemical,and the activities are influenced by many factors such as neurons form,external stimulation and temperature.It shows a very rich nonlinear dynamic behavior,which contains a variety of discharge mode and its induced mechanism.So it has been focused widely by people.International scholars carry out the research from theoretical and experimental aspects of surrounding neurons.Based on dynamic bifurcation theory to analyze cause and evolution mechanism of the neuron firing pattern is one of the important methods of researching its discharge activity at present.At the same time,along with the development of optical detection technology,various imaging technology are gradually applied to nondestructive testing and recognition of neuronal morphological characteristics and its dynamics research,which played a huge role.Surrounding the neurons bursting and based on the nonlinear dynamic analysis method and quantitative phase imaging,neurons discharge activity mechanism,light phase and morphological characteristics of neuron model on dynamic effect are studied respectively from two aspects of theory analysis and optical simulation experiment in this paper.In terms of theoretical analysis,based on the dynamic model of the two common neurons,discharge activities are studied in the different stimulating condition.That is,for neurons Hindmarsh-Rose model,different discharge mode and evolution of clusters of system under constant stimulation are simulated through numerical calculation.And modulation effect of the system discharge behavior on external stimulus and other parameters is comparative analyzed.For piecewise linear Izhikevich neurons model,the emergence and evolution mechanism of cluster model under the period stimulus are researched by the analysis of the bifurcation.In simulation experiment research,starting from the essence of the neurons discharge activity and dynamical features,based on the correlation among the ion concentration,refractive index and phase shift,neurons optical phase model isestablished and its phase distribution information in different directions is obtained through the optical phase imaging simulation technology.Then the structure characteristic of the model is analyzed by using the phase gradient,and the dynamic effect of discharge activities on phase information is considered.Starting from the change of index refraction of sample,the change of the phase information under its modulation methods of characterization is preliminarily discussed.Finally,the research work is summarized and the future research work is prospected in the paper.The modulation mechanism of its discharge activities under the periodic external stimulation is revealed through the analysis of the dynamic model in the paper,which provides the reference to study the regulation of neurons firing pattern and the fastslow coupling movement mechanism of autonomous power system.The morphological characteristics and free marking visual inspection of discharge activities of neurons are studied from the angle of the phase imaging.Then neurons optical phase model is established.The preliminary dynamic characterization of refractive index is carried on with the phase information,which provides certain basis for research method under the optical phase parametric expression of neuronal discharge activities.