Analysis Of Clinical Characteristics Of Senile Epileptics

Objective:To investigate the classification of seizures, etiology,EEG examination,treatment and prognosis of senile epileptics.Methods: The clinical data of 92 senile epileptics in The Second Affiliated Hospital Of Chongqing Medical University from January 2012 to September 2015 were retrospectively analyzed.Results: From the selected sample, 15 cases suffered from SPS(16.3%),22 cases suffered from CPS(23.9%),40 cases suffered from GTCS(43.5%),4 cases from partial seizures with secondary generalization(4.3%),11 cases from both partial seizures and generalized seizures(12.0%).The common causes include cerebrovascular disease(57.6%),intracranial tumors(10.9%), degenerative brain diseases(7.6%) and so on.The abnormal ratio of REEG and AEEG was 87.1% and 91.7% respectively.The ratio of typical epileptiform activity in the REEG and AEEG was 22.6% and 70.8% respectively.82 cases(89.1%)were treated with AED,but only 69 cases had been taking orally AED among the patients with AED.57 cases(82.6%) were on monotherapy.55 cases(67.1%) were controlled effectively with drug treatment,11 cases(13.4%) were ineffective and 16 patients(19.5%) died. Advanced age was the important cause of death. Age was positively correlated with the fatality rate(Spearman correlation coefficient was 0.314,P=0.002).9 cases(10.9%) appeared side effect,the frequency of sleepiness was the highest among all the adverse reactions.Conclusion:The majority of senile epileptics suffer from symptomatic epilepsy,the main cause is cerebrovascular disease,the generalized tonic-clonic seizures constituted a high proprotion in the sample.The ratio of typical epileptic discharge in the REEG was low from senile patients with epilepsy,we recommend the AEEG examination in the senile patients suspected with epilepsy. AED has excellent therapeutic effects in senile epileptics,and a few patients appeared light adverse reactions.