| Purpose:Through researches on patients with different syndromes of BPV(blood pressure variability) hypertension to investigate its characteristics and influencing factors, it provides the basis for the treatment of hypertension under traditional Chinese medicine and improves autonomic nervous function preventing cardiovascular and cerebrovascular incidences.Methods: a sample with 380 patients of syndrome of hypertension from June 2014 to December 2015 in cardiovascular disease and hypertension sleep department of the Affiliated Hospital of Gansu University of Chinese Medicine was observed in a cross-sectional way. It collected the general information of patients, clinical symptoms, BPV index data, on the basis of "Chinese medicine treatment of hypertension clinical research guiding principle", "vertigo disease(hypertension) program(Trial Implementation of clinical pathway of traditional Chinese medicine"). They were divided into hyperactivity of Yang due to yin deficiency syndrome, phlegm and blood stasis syndrome, phlegm dampness Yun Sheng syndrome, kidney qi deficiency, deficiency of Qi and blood deficiency syndrome, hyperactivity of liver fire excess syndrome, syndrome of deficiency of both yin and Yang seven syndrome group, compared the change characteristics and influencing factors of different types of BPV, and statistically using the Wilcoxon rank sum test multiple stepwise regression analysis.Results: 1. The syndrome of the-above-mentioned 380 patients is accordingly distributed as follows : 146 cases of hyperactivity of Yang due to yin deficiency(38.42%), phlegm and blood stasis syndrome in 122 cases(32.11%), phlegm dampness Yun Sheng syndrome 36 cases(9.47%), kidney qi deficiency syndrome in 30 cases(7.89%), Qi and blood deficiency syndrome 20 cases(5.26%), hyperactivity of liver fire excess syndrome in 14 cases(3.68%), 12 cases of deficiency of both yin and Yang(3.16%) 2. Patients with different syndrome of BPV hypertension changes suggestive, phlegm and blood stasis syndrome in patients with 24 h MSBPSD, DMSBPSD and other card type were significantly higher, the difference was statistically significant(P< 0.05); the patients with deficiency of Qi and blood deficiency syndrome, phlegm and blood stasis syndrome, yin deficiency and yang hyperactivity syndrome 24 h MSBPCV, 24 h MDBPCV, DMSBPCV, DMDBPCV, NMSBPCV, NMDBPCV with phlegm dampness Yun Sheng syndrome andkidney deficiency syndrome was significantly higher, the difference is statistically significant(P< 0.05); Yin deficiency and yang hyperactivity syndrome of NPP and other card type were significantly higher, the difference is statistically significant(P< 0.05). The 24 h MSBP, 24 h MDBP, DMSBP, DMDBP, NMSBP, NMDBP, 24 h MDBPSD, DMDBPSD, NMSBPSD, NMSBPSD, 24 MPP, DPP, systolic pressure / diastolic blood pressure of nocturnal blood pressure decline rate, and morning blood pressure peak do not show significant difference between the two groups(P< 0.05). 3. Concerning 15 potential factors such as gender, age, smoking, alcohol consumption, coronary heart disease, hyperlipidemia, stroke, diabetes, they may affect BPV hypertensive patients by multiple linear regression analysis. The conclusion was shown that Yin Yang hyperactivity BPV(24h MSBPSD,24 h MSBPCV,24 h MDBPCV,NPP) patients with age, coronary heart disease, COPD, OSAHS, insomnia, excessive intake of salt, alcohol and other factors are positively correlated(P<0.05); phlegm Syndrome BPV(24h MSBPSD,24 h MSBPCV,24 h MDBPCV) with age, diabetes, OSAHS, excessive intake of salt, alcohol, hypertension degree of risk, HHCY and other positive correlation(P<0.05); phlegm Yun Sheng Syndrome BPV(24h MSBPSD,24 h MSBPCV,NPP) patients with COPD, emotional agitation, hypertension degree of risk, HHCYand other factors are positively correlated(P<0.05); kidney deficiency syndrome BPV(24h SBPSD,24 h MSBPCV) patients with diabetes,alcohol and other factors are positively correlated(P<0.05); blood deficiency syndrome BPV(24cch SBPSD,NPP) was positively correlated with patient age, coronary heart disease, insomnia(P<0.05).Conclusion:1. The syndrome of the patients with BPV hypertension was distinct. Alongsidehyperactivity of Yang due to yin deficiency syndrome, phlegm and blood stasis syndrome,deficiency of qi and blood syndrome, the changes on the patients were obvious. 2.Age,Excessive intake of sodium salt, alcohol, coronary heart disease,COPD, diabetes andother factors affect differently the BPV parameters, leading to 24 h MSBPSD, 24 h MSBPCV,24 h MDBPCV, NPP being increased. |
