| Objective: This study was designed to explore the prevalence and the risk factors of major depressive disorderand anxiety disorder among people living with HIV/AIDS in Guangdong, to investigate the impact of demographic characteristic, HIV related characteristic, negative life events and social support on major depressive disorder and anxiety disorder, and to provide empirical evidence for mental health assessment and intervention work among people living with HIV/ AIDS in Guangdong.Methods: A cross-sectional study was carried out on Three hundred and thirty nine PLWHA who were eighteen years or older in Guangzhou, Zhongshan, Yangjiang in Guangdong province. The subjects were administrated a face-to-face interview that obtained information about demographic characteristic,HIV related characteristic, negative life events and social support by using Social Support Rating Scale(SSRS) and 17 item negative life events scale, respectively. Three hundred and thirty nine PLWHA were assessed with the structured clinical interview for the diagnostic and statistical manual of mental disorders(DSM-IV) Axis I disorders(SCID) by two licensed clinical psychologists to generate diagnosis of major depressive disorder and anxiety disorder. Then Hamilton Depression Rating Scale(HAMD) and Hamilton Anxiety Rating Scale(HAMA) was used to evaluate the severity of major depressive disorder and anxiety disorder. The prevalence of major depressive disorder and anxiety disorder among people living with HIV/AIDS was calculated. T test was used to compare continuous variables, Chi-squared tests for categorical variables and Mann-Whitney test for non-normal distribution variables. Multivariate logistic regression was performed to explore risk factors associated with major depressive disorder and anxiety disorder among people living with HIV/AIDS.Results: Among the 339 respondents, the mean age(SD) was 34.5(7.1) years. 82.6% were male and 38.6% were married. The prevalence of major depressive disorder among people living with HIV/AIDS were 12.1%(current) and 22.7%(lifetime).Among people living with HIV/AIDS who were diagnosed with current major depressive disorder, 79.5% have mild to severity depressive symptoms. The prevalence of anxiety disorder among people living with HIV/AIDS was 30.1%(current) and 27.1%(lifetime). 62.9% have mild to severity depressive symptoms. The prevalence of comorbidity was 6.8%. Multivariate analysis showed that, Patients diagnosed with AIDS(OR=2.46,95%CI:1.10~5.50) and high chronic stress score resulting from negative life events(OR=25.01,95%CI:3.27~191.2) was independent risk factor for major depressive disorder among people living with HIV/AIDS, while the education level(OR=0.32,95%CI: 0.13~0.77) and high chronic stress(OR=2.85,95%CI:1.53~5.32) were significantly associated with anxiety disorder, respectively.Conclusion:(1)People living with HIV/AIDS appear to have a significantly increased risk for major depressive disorder and anxiety disorder, suggesting a need of mental health among People living with HIV/AIDS, and develop a psychological crisis evaluation programme and intervention for them.(2)Negative life event was common risk factors of major depressive disorder and anxiety disorder among people living with HIV/AIDS. Educational level was independent risk factors of anxiety disorder. The lower educational level, the higher risk for developing anxiety disorder. Patients diagnosed with AIDS were more risky in developing major depressive disorder than people living with HIV. |
