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The Risk Factors Of Upper Gastrointestinal Bleeding And The Risk Assessment Of Non-variceal Upper Gastrointestinal Bleeding

Posted on:2016-11-07Degree:MasterType:Thesis
Country:ChinaCandidate:J M ChenFull Text:PDF
GTID:2284330503951898Subject:General medicine
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Objective To investigate the risk factors of upper gastrointestinal bleeding and the risk assessment of non- variceal upper gastrointestinal bleeding.Methods Clinical data of 140 patients with upper gastrointestinal bleeding from January 2013 to January 2014 were co llected from department of emergency medicine of Tianjin medical university general hospital, including 121 patients with non- variceal upper gastrointestinal bleeding. Gender, etiology, inducement, laboratory data, length of inpatient stay were collected. According to age, the patients were divided into three groups. The data included history of systolic blood pressure, pulse, melena, syncope, liver disease, heart failure, blood urea nitrogen, hemoglobin for each patient in the form of interventions[1]. These data were used to calculate the GBS scores for each enrolled patient. Using the SPSS statistical package for data analysis, the qualitative variables using chi-square test, p<0.05, the difference was statistically significant.Results(1)The incidence of the most common in the older group, accounting for 45.0%, followed by middle-aged group, accounting for 32.9%, less youth group. The ratio of male to female patients was 2.8:1.(2)A total of 140 patients with diagnosis of UGIB, the most common causes followed by peptic ulcer, acute gastric mucosal lesion, esophageal and gastric varices and gastrointestinal cancer, accounting for 81.43%, most common in peptic ulcer, dominated by duodenal ulcer, followed by acute gastric mucosal lesion and esophageal and gastric varices in youth group; followed by esophageal and gastric varices and gastrointestinal cancer in middle-aged group; followed by acute gastric mucosal lesion and gastrointestinal cancer in the older group.(3)Youth, the middle-aged group are the first inducement of improper diet is, while the older group first inducement because of aspirin.(4)The majority of patients with upper gastrointestinal bleeding initial symptoms were melena and haematemesis, accounting for 33.6%; followed by melena, accounting for 30.7%; less haematemesis, accounting for 12.1%.(5)Inpatients from 7 to 14 days occupied 55.0%; followed by less than 7 days, less for more than 14 days. The most common in the o lder group, accounting for 25.8%; followed by the middle-aged group, accounting for 25.5%; less youth group, accounting for 3.3%.(6)Collecting 140 patients with UGIB, a higher prevalence in winter, accounting for 42.1%; the second season is autumn, accounting for 26.4%; the third is summer, accounting for 20.0%; the least is spring, accounting for 11.4%.(7)121 patients with NVUGIB were enrolled and analyzed. The clinical Blatchford score identified 7 patients as low-risk and 20 patients as high-risk in youth group. while identifying 5 patients as low-risk and 31 patients as high-risk in the middleaged group; and identified 10 patients as low-risk and 48 patients as high-risk in the older group. The Blatchford score identified 99 of 121 patients as high-risk. 3 patients were recorded in the low-risk group identified by a GBS of 0. In the prediction intervention for transfusion, the area under the ROC curve of the Blatchford score was 0.63, which was effective.Conclusion 1.There are gender differences in patients with upper gastrointestinal bleeding, men were more than women. 2.The cause of upper gastrointestinal bleeding is different,due to peptic ulcer, dominated by duodenal ulcer, followed by acute gastric mucosal lesion and esophageal and gastric varices in youth group; followed by esophageal and gastric varices and gastrointestinal cancer in middle-aged group; followed by acute gastric mucosal lesion and gastrointestinal cancer in the older group. 3.Upper gastrointestinal bleeding have a high incidence of seasonal, winter. 4.The Blatchford score is suitable for non-variceal upper gastrointestinal bleeding. The GBS performed best in predicting intervention for transfusion.
Keywords/Search Tags:upper gastrointestinal bleeding, non-variceal upper gastrointestinal bleeding, Glasgow-Blatchford Bleeding Score, risk factors, risk assessment
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