The Application Of Narcotrend In The Monitoring Of Laparoscopic Cholecystectomy

ObjectiveTo evaluate the accuracy, practicability and clinical significance of Narcotrend in the monitoring of laparoscopic cholecystectomy(LC).MethodsSix hundred patients who received selective LC under general anesthesia were randomized divided into Narcotrend group and Control group(300 cases each group). The depth of anesthesia was adjusted by the Narcotrend monitor in Narcotrend group, assigned to expect Narcotrend index of 37-56. The depth of anesthesia was adjusted according to the clinical experience in Control group. The amount of bleeding, drug use,awakening time and the level of MAP and HR on the time-point of 10 min before induction(T0), 3 min after induction(T1), intubation moment(T2),skin incision(T3), 3 minutes after CO2 pneumoperitoneum(T4), end of surgery(T5), extubation moment(T6) were recorded. After the operation,the end of operation over to the time of tracheal extubation, the time of PACU, the incidence of intraoperative awareness were noted down.Results1)Compared with Control group : HR on the time-point of T2,T4,T6 in Narcotrend group were statistically significant( P<0.05). MAP on the time-point of T2,T4 in Narcotrend group were statistically significant( P<0.05).2)Compared with Control group :The awakening and extubation time in Narcotrend group were shorter,the differences were statistically significant( P<0.05), The dosage of propofol and sufentanil in Narcotrend group were smaller,the differences were statistically significant( P<0.05).3) Compared with Control group :The incidence of intraoperative awareness in Narcotrend group was lower,but had no statistical significance( P>0.05).ConclusionThe application of Narcotrend monitoring in laparoscopic cholecystectomy can make vital signs during operation more steady,reduce the dosage of anesthesia drugs, shorten the recovery time,paobably can prevent intraoperative awareness to some extent, having guiding significance for anesthetic drugs and management.