| Objective:Retrospective analysis basic clinical data of 2012-2014 inpatients with atrial fibrillation(AF) in Cardiovascular Medicine Department and Geriatric Department of first affiliated hospital of Xinjiang shihezi University. Aim to investigate its fundamental clinical characteristics, risk factor, antithromboembolism treatment, antiarrhythmic treatment and upstream treatment of the hospitalized patients with AF in order to provide a reference for future clinical treatment of hospitalized patients with AF.Methods:Using the center of the first affiliated hospital of shihezi University School of medicine network electronic medical record management system, according to the international classification of diseases for ICD-10 coding, retrieved clinical information of 750 cases with AF,the patients admitted in our hospital in Cardiovascular Medicine Department and Geriatric Department during 2012- 2014. Record its fundamental clinical characteristics, risk factor, thromboembolic complications and drug treatment situation for statistical analysis.Statistics:Use Epidate3.1 to set up database, SPSS17.0 statistical software to data analysis, express the enumeration data of normal distribution as mean ±standard deviation, the enumeration data was used the chi-square test, and P<0.05 was considered statistically significant.Result:1.There was a total number of 750 cases of hospitalized patients with AF, the average of age was 69.7years old, The age of patients ranged between 24 to 94. The proportion of male was 60.4%, and female was 39.6%. The ratio of male to female was 1.5:1. proportion of patients below 60 years old was 33.9%, highest percentage of 60~74 years old, was49.7%,proportion of patients over 75 years old down to 33.9%.2. In the uni-factor analysis of AF, the top causes followed by coronary heart disease(68.3%), hypertension(56.7%),Pulmonary disease(30.5%),diabetes(23.9%), and heart failure(22.4%).The proportion of rheumatic heart disease was 6.27%. The percentage of coronary heart disease, high blood pressure, heart failure and respiratory diseases gradually increased with age; the proportion of rheumatic heart disease, and cardiomyopathy gradually decreased, there was a statistically significant difference.3. According to the age groups, The top three causes in patients under 60 years-old followed by hypertension(45.4%), CHD 33.1%, cardiomyopathy(21.5%); the main causes of from 60 to75 years old group followed by CHD(72.4%), hypertension(60.6%), anddiabetes(25.5%).60-75; over 75 years old was CHD(80.6%) hypertension(67.6%), heart failure(27.5%).4. Divided By gender, more male than male under age 60, in age 60-74 most were female patients. Over the age of 75 were more male than female(P<0.05). atrial fibrillation combine congestive heart failure and rheumatic heart disease, more female than male(P<0.05), atrial fibrillation combine respiratory diseases male than female(P<0.05). The proportion of valvular AF was 13.5%, and non-valvular AF was 86.5%.The proportion of female in valvular AF was significantly higher than the non-valvular AF(P <0.05).5. Rheumati VAF was 6.2%, NVAF was 86.3%. the proportion of female of NVAF was significantly higher than male. NVAF with larger left atrium, faster heart rate. VAF more has hypertension, coronary heart disease.6. In the antithrombotic therapy of patients with AF,the proportion of without antithrombotic therapy was 68.4% in all patients. Aspirin accounted for 33.3%, and aspirin +clopidogrel accounted for 30%.The proportion of the patients treated with warfarin was35.2% of all patients. Divided by sex, male and female has no different in antithrombotic therapy.Divided by age, the proportion of using antithrombotic was increased by age,but warfarin was decreased.7. In the treatment of antiarrhythmic,14.3% without any treatment; the proportion of drug cardioversion(rhythm control) was 17.6%;the proportion of rate control more than cardioversion. The proportion of the top three antiarrhythmic treatment followed by beta-blockers(75.2%), digitalis(37.7%) and CCB(33.1%).8. In the upstream treatment of AF, the application of statins was 80.3% of all the patients,nitrates(39.6%), ACEI(62.1%), and diuretic(42.4%).9. During in the hospital, there were serious complications,mainly include severe bleeding events, stroke, death, and the incidence were 4.1%, 4.3%, 1.6%.Conclusion:1.The dominent AF patients in our hospital was old men. 2.The major risk of AF in this study were coronary Heart disease、Hypertension、Respiratory disease、Diabetes and Heart failure;The elder main had coronary heart disease and Hypertension. 3.The major antithrombotic therapy of patients with AF in our hospital was antiplatelet; The anticoagulant therapy rate went down the older a person get.;In the upstream treatment of AF, the rate of statins was notable. |
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