Prevalence Of Protein-energy Wasting Syndrome And Its Association With Serum Uric Acid In Non-dialysis Patients With Chronic Kidney Disease

Objective:The aim of this study was to examine the prevalence PEW and its association with serum uric acid in non-dialysis patients with chronic kidney disease, and to provide the theoretical basis for prevention of protein-energy wasting in chronic kidney disease.Methods:Retrospective analysis of the data in Shanxi Medical University the first clinical medical college of 2014 to 2015 years 11 months with patients: showed that CKD patients with 105 cases, according to the serum uric acid level divided into the normal uric acid group 59 cases, high uric acid group 46 cases. General data collection, detection of total protein(TP), albumin(ALB), and serum total cholesterol(TC), serum triglyceride(TG),fasting plasma glucose(FPG), fasting insulin(FINS), hemoglobin A1c(Hb A1c),urea(urea),creatinine(CRE), uric acid(UA), to calculate body mass index(BMI), insulin resistance index(HOMA- IR), the statistical analysis and comparison of two groups of clinical indicators of differences.Results:Statistical analysis shows that bases, HUA group and normal group,with TP, ALB,TC, TG, HDL-C, LDL-C levels were no statistical significance(P > 0.05); but levels of fasting plasma glucose(P= 0.001), fasting insulin(P= 0.005), serum uric acid(P=0.002),creatinine levels(P=0.035), body mass index(P=0.032)and insulin resistance index( P=0.001) was significantly higher than that of the normal group, the difference has different(P < 0.05).Conclusion:Prevalence of protein-energy wasting syndrome and its association with serum uric acid in non-dialysis patients with chronic kidney disease,and to provide the theoretical basis for prevention of protein-energy wasting in chronic kidney disease.