The Clinical Effect Study Of Thromb Ectomy With Solitaire AB Stenton Treating Acute Cerebral Infarction

Objective:To investigate the effect and safety of thrombectomy with Solitaire AB stent in treating acute cerebral infarction.Methods:(1) Choosing 66 patients of acute cerebral infarction from December 2014 to December2015 in our hospital. All of the patints were excluded cerebral hemorrhage by CT examination and Confirmed Intracranial artery occlusion by CTA. The time is 3-17 hours from the onset to treatment. In which 46 cases of family members signed informed consent, received stent thrombosis treatment, From which 20 patients were selected as thrombectomy group(Treatment of anterior circulation occlusion in 8 hours, and posterior circulation occlusion in 24 hours), 1 cases were given intravenous thrombolysis before the time window was taken, and then bridged for mechanical thrombectom. The remaining 20 patients refusing treatment of thrombectomy were treated with intravenous thrombolysis and drug conservative therap as control group, 4 cases choose thrombolytic therapy within time window.Time out of the window of the patients to choose the traditional conservative treatmentt. Determining the inclusion criteria and the exclusion criteria, and there were no significant difference between the two group in stroke risk factors such as age, sex,and background disease(high blood pressure, diabetes, and hyperlipidemia). The difference of the NIHSS score was not statistically significant(P> 0.05) between the Two groups of patients before treatment.The Constituent ratio of the Cause of disease(the occlusion site of the intracranial vascular) is basically consistent.(2) Efficiency Analysis:the Evaluation of two groups of the vascular recanalization is by TICI and CTA.the Improvement of neurological symptoms are compared by NIHSS. The evaluation of long –term efficacy is by m RS. the m RS ≤ 2 of the patients are good prognosis.we compare the proportion of patients with m RS score of ≤2.(3) Safety Analysis: Comparing the two groups of patients with intracranial hemorrhage incidence and mortality.Results:Efficiency:( 1) Recanalization rate: Thrombectomy group recanalization is 90%,thrombolytic recanalization group is 25%,and there is a statistically significant difference(P <0.05).(2) NIHSS score: The NIHSS scores of 24 hours after treatment and 2 weeks after treatment are(14.6±3.9),(6.2±2.7) in the thrombectomy group,and control group are(17.4±4.2)、(9.3±3.5). The differences are statistically significant(P <0.05) between the two groups.(3) m RS score: the proportion of patients with m RS score of ≤2 in the thrombectomy group is significantly higher than the control group.Safety: Thrombectomy group and thrombolysis group compared with the rate of intracranial hemorrhage, the difference is not statistically significant(P>0.05).Thrombectomy group and thrombolysis group compared with the mortality rate, the difference is statistically significant(P> 0.05).Conclusion: Acute cerebral infarction caused by Intracranial artery occlusion using stents compared with traditional intravenous thrombolysis and conservative treatment can significantly improve the recanalization rate, the clinical symptoms and the long-term prognosis of patients, And does not increase the intracranial hemorrhage and mortality of patients.