| Objective: This research is used for analyzing the pregnancy outcome of cervical cone cutting operative.Methods: A retrospective study was performed of patients who were operated cervical cone cutting from 2007 to 2012, meanwhile, compared with the 80 patients who was not operated by cervical cone cutting. At the same time, the effect of different operation type to the pregnancy outcome was compared. In this research, the main indexes were included as followed: a. pregnancy outcomes: no contraception pregnancy time, no pregnancy, early abortion, late abortion, Natural birth and cesarean delivery; b. obstetric outcomes: term premature rupture of membranes, preterm labor, and fetal growth restriction.Results: The pathological results of cone biopsy surgery colposcopy: CIN I 17 cases, CIN II 21 cases and CIN III 40 cases. Postoperation pathology results showed: CIN I 13 cases, the coincidence rate was 76.5% with CIN I lesions consistent with colposcopy; CIN II 16 cases, CIN II lesions with colposcopy coincidence was 76.2%; CIN III 36 cases, the coincidence rate was 90.0% with CIN I. The total coincidence rate was 83.3% between pathology and colposcopy biopsy results after surgery. In the surgery group, 65 of 78 cases were pregnancy, and the pregnancy rate was 83.33%; While in the control group, 72 of 80 women of childbearing age were pregnancy, and the pregnancy rate was 90.00%. It showed no significant difference between the two groups(χ2 = 1.523, P = 0.217). In the small cone depth group, 34 of 39 cases were pregnancy, and the pregnancy rate was 87.18%; in the large cone cut deep group, 31 of 39 cases were pregnancy, and the pregnancy rate was 79.49%. It showed no significant difference in the two groups(χ2 = 0.831, P = 0.362). In the small cone perimeter group 33 of 39 cases were pregnancy, the pregnancy rate was 84.62%; in the large cone perimeter group, 32 of 39 patients were pregnancy, the pregnancy rate was 82.05%. It showed no significant difference between the two groups(χ2 = 0.092, P = 0.761). In the surgery group 78 patients delivered 56 fetuses, accounting for 71.79%; in the control group, 80 women of childbearing age delivered 69 fetuses,accounting for 86.25%. There were significant differences between the two groups(χ2 = 4.994, P = 0.025). It indicates that conization of cervix surgery can reduce the birth rate. In the small cone depth group, 33 of 39 patients delivered 33 fetuses, accounting 84.62%; in the large cone cut deep group of 39 patients delivered 23 fetuses, accounting for 58.97%. Fetus rate in the large cone depth group was significantly lower than that in the small cone depth group(χ2 = 6.331, P = 0.012). In the small cone perimeter group, 39 cases delivered 33 fetuses, accounting for 84.62%; in the large cone perimeter group, 39 patients delivered 23 fetuses, accounting for 58.97%. Fetus rate in the large cone perimeter group was significantly lower than that in the small cone perimeter group(χ2 = 6.331, P = 0.012).Conclusions: CKC surgery does not reduce the desire of pregnancy in patients with pregnancy. Different cone depth and desire of pregnancy in patients with pregnancy-independent. Different cone depth indifference to extend time without contraception pregnancy. Different cone perimeter and desire of pregnancy in patients with pregnancy-independent. Different cone perimeter was no difference for the extension of time without contraception pregnancy.Conization of cervix surgery can reduce the birth rate. Conization can significantly reduce the rate of fetal term delivery, conization can significantly increase the rate of preterm birth, conization surgery can significantly increase the incidence of premature rupture of membranes. Increasing the depth of conization will reduce the fetus rate, increase in the rate of preterm birth group of small cone depth, and increase the incidence of premature rupture of membranes.Increasing the cone perimeter will reduce the rate of the fetus, reduce the full-term birth rate and increase the incidence of premature rupture of membranes. |
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