Study On The Correlation Between Blood Lipid Level And Abdominal Aortic Aneurysm Disease Risk

Objective:Studying on the clinical application value of blood lipid ratio and individual blood lipid index in the risk of abdominal aortic aneurysm by comparing the differences of serum lipid levels and lipid ratios between abdominal aortic aneurysm patients and healthy controls.Methods:During the period of the First Affiliated Hospital of Kunming Medical University from March 2013 to March 2016,55 patients with AAA and excluding coronary heart disease patients (case group) compared with 61 healthy controls(control group). There was no significant difference in gender, age, blood pressure, smoking status and other general data, and the difference was not statistically significant(P>0.05). Triglyceride (TG),total cholesterol (TC), high density lipoprotein (HDL-C), low density lipoprotein (LDL-C), TC/HDL, TG/HDL /,LDL/HDL were observed in the study. According to the first diagnosis when the maximum diameter of the tumor, they were divided into>4cm and≤4cm two groups, compared two groups of blood lipid levels.Results:Comparing AAA group with control group, TG was significantly increased, and the difference is highly statistically significant (P< 0.01); TC/HDL, LDL/HDL was significantly higher, the differences were statistically significant (P< 0.05); There was no significant difference in TC, LDL, HDL and TG/HDL between the two groups (P>0.05). LDL, HDL, TC, TG, TC/HDL,TG/HDL,LDL/HDL showed no significant difference between the two groups (<4cm and>4cm). The AUC of TG is larger than LDL/HDL and TC/HDL. Conclusion:Triglyceride elevation is a risk factor for abdominal aortic aneurysm, and the detection of triglyceride in serum can provide a basis for prevention, diagnosis and treatment of abdominal aortic aneurysm. Blood lipid ratio (TC/HDL-C, LDL-C/HDL-C) has a certain clinical value for early prevention and diagnosis of abdominal aortic aneurysm. However, in relation to the abdominal aortic aneurysm, the triglyceride is higher than the blood lipid ratio. The incidence of abdominal aortic aneurysm is a common result of multiple factors, and the weight of dyslipidemia in the incidence of abdominal aortic aneurysm needs further research.