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The Research O Pulmonary Ventilation Function Of Patients With Lower Inferior Right Lung Cancer Radical Operation Between Traditional Open Surgery And Video-assisted Thoracic Surgery

Posted on:2017-03-03Degree:MasterType:Thesis
Country:ChinaCandidate:C X XiongFull Text:PDF
GTID:2284330488996870Subject:Oncology
Abstract/Summary:
Objective:Measuring the ventilation in patients with preoperative and postoperative pulmonary ventilation function, comparing to the change of pulmonary ventilation function in traditional open surgery patients with lower lobe right lung cancer radical surgery,the change of Video-assisted thoracic inferior lobe right lung cancer radical surgery in patients with pulmonary ventilation function, the contrast of lung ventilation function between traditional open surgery and Video-assisted thoracic surgery of inferior lobe right lung cancer patients after operation, to explore the influence of different operation mode on the ventilation function of patients with lung cancer.Methods:Third affiliated hospital of Kunming medical university thoracic surgery admitted inferior lobe right lung cancer patients during the period of January 2015 to February 2016, according to their condition and operative indication are divided into traditional open surgery group (TOS) and Video-assisted thoracic surgery group(VATS), patients are examined with lung function preoperative, intrathoracic surgery operation to look straight completely, according to National Comprehensive Cancer Network(NCCN) of lung resection and lymph node cleaning completely, Video-assisted thoracic surgery group of patients with intrathoracic operation are same completely with traditional open surgery group, according to standard guide line of lung resection and lymph node cleaning,the operating sequence are same with traditional open surgery group.After 1 week,1 month,3 months,6 months patients examined with lung function, collecting 2 groups of patients preoperative and postoperative lung function data, Germany, as monitoring instruments, Detecting the vital forced vital pulmonary capacity (FVC)、forced expiratory volume in one second, (FEV1)、Maximum minute ventilation(MVV) as function evaluation data.In order to reduce the error caused by using SPSS 17.0 software analysis the above data.two groups comparing with independent samples t test, measurement data is adopt mean ±standard deviation (X±S), preoperative and postoperative use of matched pairs sample t test in the group, P< 0.05, there was no statistical significance.Results:1、43 cases of lower lobe right lung cancer patients through traditional open surgery,48 cases of lower lobe right lung cancer patients through Video-assisted thoracic surgery, the two groups patients have no statistical differences in terms of gender, age, P> 0.05.2、FVC%,FEV1%, MVV% of preoperative TOS group is (102.20±32.01)%, (109.33±32.57)%,(99.40±28.53)% respectively. FVC%, FEV1%, MVV% of preoperative VATS group is (100.28±22.91)%, (111.19±19.92)%, (98.26±20.73)% respectively; P>0.05, there was no statistically significant difference between the groups.3、FVC%,FEV1%, MVV% of postoperative of TOS group is (44.58±9.61)%, (53.89±7.26)%, (54.35±7.18)% respectively after 1 week,For moderate restrictive ventilation dysfunction, P< 0.05, there was statistical Significance.4、FVC%,FEV1%, MVV% of postoperative TOS group is (63.49± 19.44)%, (71.89±20.15)%, (71.42±20.04)% respectively after 1 month, for moderate restrictive ventilation dysfunction, P< 0.05, there was statistical significance.5. FVC%,FEV1%, MVV% of postoperative TOS group is (73.73±14.04)%, (76.41±19.58)%, (79.05±18.21)% respectively after 3 months, for mild restrictive ventilation dysfunction, but have been close to the normal pulmonary ventilation function index, P> 0.05, there was no statistical significance.6、FVC%,FEV1%, MW% of postoperative TOS group is (78.23±11.82)%, (87.63±14.51)%, (84.08±14.16)% respectively after 6 months, basic returned to normal pulmonary ventilation function index, P> 0.05, there was no statistical significance.7、FVC%,FEV1%, MVV% of postoperative VATS group is (47.55±5.16)%, (58.85±9.26)%, (60.35±3.18)% after 1 week, for the moderate restrictive ventilation dysfunction, P< 0.05, there was statistical significance.8、FVC%,FEV1%, MW% of postoperative VATS group is (68.37±22.34)%, (75.40±22.78)%, (75.43±27.71)% respectively after 1 month, for mild restrictive ventilation dysfunction, P< 0.05, there was statistical significance.9、FVC%,FEV1%, MW% of postoperative VATS group is (75.32± 12.82)%, (77.47±5.62)%, (83.97± 17.04)% respectively after 3 months, has been basically returned to normal pulmonary ventilation function index, P> 0.05, there was no statistical significance.10、FVC%,FEV1%, MVV% of postoperative VATS group is (82.±17.98)%, (91.94±26.66)%, (88.60±7.35)% respectively after 6 months,has been returned to normal pulmonary ventilation function, P> 0.05, there was no statistical significance.In a word,FVC%,FEV1%, MVV% of VATS group and TOS group postoperative are reduced to some extent, but TOS group decreased more significantly, VATS group of pulmonary function postoperative after 1 week and 1 month are superior to the TOS group, P< 0.05, there was statistical significance,VATS group and TOS group postoperative pulmonary function 3 month and 6 month are close, P>0.05, there was no statistical significance.Conclusions:Pulmonary function of VATS patients postoperative recovery better recently, Video-assisted thoracic surgery has smaller influence on early postoperative pulmonary ventilation function in patients,is superior than traditional open surgery, but long-term recovery of pulmonary ventilation function between the two groups has statistical significance. Therefore, Video-assisted thoracic surgery reduces surgical trauma, protects the patient’s pulmonary ventilation function has certain advantages, which is worth promoting.
Keywords/Search Tags:inferior lobe of right lung cancer, Traditional open surgery, Video- assisted thoracic surgery, Pulmonary ventilation function
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