| Purpose:Understanding the epidemiological status of Mycoplasma pneumoniae Encephalitis, exploring and analyzing the characteristics and clinical manifestation of Mycoplasma pneumoniae Encephalitis in children, in order to facilitate early diagnosis and treatment.Methods:Selecting 706 cases of Mycoplasma infection children,26 cases of Mycoplasma pneumoniae children with viral encephalitis from October 2013 to October 2015 as the object of study, retrospectively analyzing the children’s characteristics, clinical manifestations, laboratory and supplementary examinations, treatment and prognosis.Result:During the 706 cases of Mycoplasma pneumonia infection, there are 26 cases of Mycoplasma pneumonia children with viral encephalitis. MP encephalitis incidence is 3.7% of MP infections. There are respectively 14 male cases and 12 female cases of Mycoplasma pneumonia children with viral encephalitis aging from 3 to 12 years, averaging 7.5 years. They hospitalize 2-14 days after getting sick; the average length of hospitalization are 14 days, the clinical manifestations include fever (88.5%), headache (80.7%), vomiting (50%), eclampsia (30.7%) as well as disturbance of consciousness, mental abnormalities, blurred vision, and ataxia etc., 89% of them have respiratory symptoms during the course of the disease, and only presenting 57.6% are first symptoms.19% present with neurological manifestations as the first symptom. After diagnosis the children are taking azithromycin or erythromycin to resist infections, and methylprednisolone to reduce inflammatory reaction, partly taking intravenous immunoglobulin blocking antibody treatment, where 23 patients were cured,3 were improved and discharged.Conclusion:The clinical manifestation of Mycoplasma pneumonia Encephalitis is lack of specificity, especially those children with neurologic disease onset are difficult to diagnose, and can cause serious central nervous system damage, with a certain disability rate, therefore we need to raise clinical awareness, taking active auxiliary examinations, in order to take early diagnosis and early treatment, reducing the incidence of sequel. |