| Objective (s):Acute myocardial infarction (AMI) is one of several kinds of coronary heart disease in most easily lead to death a, in recent years, our country is a clear upward trend. At present, a large number of studies have shown that H type hypertension can lead to the occurrence of cardiovascular and cerebrovascular diseases, hypertension Hcy has synergistic effect, high rate of our country H type hypertension patients, the awareness rate low. Through retrospective analysis of clinical cases, understanding of H type hypertension and acute myocardial infarction (AMI) of plasma total homocysteine (Hcy). The correlation of blood lipid, uric acid and other indicators; to understand the correlation of H type hypertension and acute myocardial infarction incidence and coronary artery stenosis and acute myocardial infarction related risk factors, by controlling the risk factors associated with. Reduce the incidence of clinical cardiovascular disease.Methods:Selected January 2014 to 2015 April sweet Hospital Affiliated to Kunming Medical University, Department of cardiology from ward were 383 cases of primary hypertension patients complicated with coronary heart disease, according to the plasma Hcy level is divided into H H type hypertension group (Hcy is more than or equal to 10 umol/L) and non hypertension group HCY<10umol/L. According to the result of coronary angiography in patients with coronary heart disease were divided into single vessel lesion group, double vessel lesion group, multi vessel disease group. The H-type hypertension group 198 cases and 117 cases of male, female 81 cases, average age (64.00 「1 0.24) years, the AMI100 Cases and non cases AMI98; non-H type hypertension group of 185 cases,106 cases of male,79 female, average age (63.59 r9.96) years, the AMI58 cases and non AMI127.AMI patients select objects in patients with acute ST segment elevation myocardial infarction and acute non ST segment elevation myocardial infarction; non AMI patients selected objects with stable angina patients, old myocardial infarction. Single vessel coronary artery disease refers to the left anterior descending coronary artery, circumflex artery, right coronary artery and its main branches vascular stenosis 50%; double coronary artery disease refers to the left main artery and 2 to With the degree of stenosis of coronary artery and its main branches stenosis; coronary multivessel disease refers to at least 3 branch of coronary artery and its main branches stenosis is more than or equal to 50%. After admission a detailed history collection, record the patient’s gender, age, weight, height, smoking history, drinking history. Two groups of patients were admitted to hospital the next day collected in the morning fasting venous blood, by laboratory detection of Hcy, TG, TC, HDL-C, LDL-C, UA. Patients underwent coronary angiography and improve the operation record.Results:1、Two groups of patients age, gender, body mass index, smoking, alcohol consumption was not statistically significant.2、In 158 AMI patients,113 males and 45 females, the ratio of male to female was 2.5:1, The incidence of AMI in male patients was higher than that in female, and the male was earlier than female.3、①H type hypertension patients occurred in the proportion of AMI was significantly higher than that of non H type hypertension patients H type hypertension group, the plasma Hey and UA levels higher than non H type hypertension group, the difference was statistically significant. The differences of the other indicators no significant difference (P>0.05).② H type hypertension patients with AMI group, the plasma Hcy, TQ HDL-C levels were higher than non AMI patients (P<0.05), there was statistical significance. Other indexes showed no statistical differences.③ non H type hypertension in patients with AMI was blood Hcy, HDL-C levels were higher than those of non AMI patients (P<0.05), there is statistical significance There were no significant differences in other indicators.4、 By multiple regression analysis, sex, HCY, hypertension, TG and AMI were correlated (P<0.05).5、AMI patients with multivessel coronary artery disease plasma Hcy levels higher than the double vessel lesion group and single branch lesion group, the differences were statistically significant (P<0.05).AMI in patients with single vessel coronary artery disease of blood uric acid level higher than double vessel lesions group and multi vessel disease group, differences were statistically significant (P< 0.05) H type hypertension in AMI group Gensini score for 50.26 r16.84, non H type hypertension in AMI group Gensini score for 38.96 r19.36, the difference has statistical significance (P<0.05).Conclusions):1.In this study, the prevalence of AMI in male patients was higher than that in female.2.H type high blood pressure and AMI are closely related; sex, HCY, hyp ertension, AMI and TG were correlated.3.H in patients with type Hcy hypertension is related to the severity of coronary... |
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