The Effect Of Modified Buyanghuanwu Decoction On The Ventricular Remodeling Of Patients With Acute Myocardial Infarction Who Had Treated By Percutaneous Coronary Intervention(PCI), And Were Belong To Qi Deficiency And Blood Stasis In The Traditional Chine

ObjectivesrTo observe distribution of TCM (traditional Chinese Medicine) syndromes after the PCI of patients with acute myocardial infarction; evaluate the effect of Modified Buyanghuanwu Decoction on ventrivular remodeling of patients with AMI who had treated by Percutaneous Coronary Intervention(PCI), and were belong to qi deficiency and blood stasis in the traditional Chinese Medicine.Methods:Choose 160 patients with AMI who had an operation of PCI in the Vasculocardiology Deparment of TCM Hospital of Kunshan in Jiangsu province, in the eastern China. Conduct TCM syndrome differentiation and classify before and 1 week after the operation, and observe the changes of TCM syndrome types after the operation. Afterwards, randomly divide 60 patients with AMI, who suffer from qi deficiency and blood stasis after PCI, into a therapy group (n=30) and a control group (n=30). Patients in the therapy group are treated with western medicine and Modified Buyanghuanwu Decoction, while those in control group only take western medical treatment. After three-month treatment, compare the patients in both groups in terms of TCM syndrome integral, cardiac function level, and ventricular structure.Results:(1)The incident rate of qi deficiency and blood stasis type after AMI-PCI surgery is going higher than that before the operation, and patients suffer from qi deficiency and blood stasis type significantly outnumber those with other syndrome types (such as phlegm and blood stasis, cold congelation, and vital qi deficiency and yang collapse), with statistical significance (P<0.05).(2)Both groups are reported declines in TCM syndrome integral, comparing with that before the treatment (P<0.05), particularly symptom score reducing in the therapy group even more remarkable, representing statistical significance (P<0.01); LVEF in both groups increase in comparison with the pre-operation (P<0.05), and the therapy group is superior to the control group, with statistical significance (P<0.01); In comparison with the pre-operation, the BNP level declines in the two groups (P<0.05), especially more significant difference in the therapy group, which has extraordinarily statistical greatness (P<O.01); After treatment, patients in both groups are reported with the reduction in LVIDd and LVIDs levels (P<0.05). Comparing with the control group, the reduction in the therapy groups are even more significant, with statistical significance (P<0.05).Conclusion:(1) Qi deficiency and blood stasis type is the most common syndrome type diagnosed among patients with AMI after PCI.(2) The Modified Buyanghuanwu Decoction plays a significant role in improving TCM clinical symptom, enhancing cardiac function level, inhibiting or reversing ventricular remodeling.