Observation Of The Effect Of Breathing Machine In Different Body Position In Children With Acute Respiratory Distress Syndrome

[Objective] This study was designed to discuss the implementation of different postures in children ARDS on ventilator inhalation treatment; observe the effect of the two treatments in diluting the Sputum, reducing the inflammation of the lung bases and other index;compare the efficacy of two different ways of posture; and provide a reference for the standard operating procedures and care programs of prone position ventilation inhalation therapy for ARDS children.[Methods] This study was based on the 60 ARDS children in the PICU ward of Nanjing Children’s Hospital from March 2014 to March 2016. The 60 cases of children with ARDS meet the inclusion and exclusion criteria, and voluntarily joined as research subjects in this study. The children were randomly divided into experimental and control groups by a randomized controlled trial. The prone position ventilation inhalation was adopted in the experimental group, while the semi-recumbent position ventilator inhalation was adpoted in the control group. The study compared the differences of 24 hours sputum viscosity, the results of the blood gas analysis (PH, PaCO2, PaO2) on semi-supine/prone position ventilation inhalation after the first day to the seventh day, oxygen saturation, P/F ratio and the total duration of mechanical ventilation between the two groups of children. The SPSS18.0 software package was used for statistical analysis, the differences between groups were compared by chi square test or analysis of variance. P□ 0.05 was considered statistically significant.[Results] The research indicated that there was no statistically significant difference between the two groups in the aspects of gender, age, body temperature, heart rate, blood pressure, oxygen saturation and other baseline data (P>0.05). The PH value, PaCO2 and PaO2 of the two groups on board was not statistically significant within half an hour (P>0.05). Statistically significant differences were showed between the two groups in the aspects of 24h sputum viscosity in Semi-supine/prone position after inhalation of ventilator. No statistically significant difference was found between the two groups in the aspects of 24h sputum viscosity in Semi-supine/prone position after inhalation of ventilator. Oxygen saturation (SPO2) within 1-4 days showed no significant difference between the two groups, but during the 5th-7th days, the difference was statistically significant in Semi-supine/prone position after inhalation of ventilator. After the inhalation of ventilator being used in Semi-supine/prone position, there was no significant difference (P>0.05) between the two groups in blood gas analysis (PH, PaCO2, PaO2) during the 1st-7th days, however, the difference was statistically significant in P/F ratio during the sixth and seventh days. The total time of mechanical ventilation in the experimental group of children was shorter than the children in the control group; the difference was statistically significant (P<0.05). There were no complications in the two groups.[Conclusions] Prone position ventilation inhalation treatment is an ideal treatment. It can improve oxygenation index more effectively, correct hypoxemia, dilute sputum, improve sputum viscosity and reduce inflammation of lung bases.