The Study Of Preoperative CT Perfusion Imaging On The Clinical Evaluation Value Of Glioma Resection

Objective: Investigating the clinical value of preoperative CT perfusion imaging to guide resection of glioma, discuss and analyze those date which have statistical significance, With the current common methods which surgical tumor extent determined by CT as a reference, we could analyze and summarize the recurrence rate of patients whose surgical tumor extent determined by perfusion in our hospital, then to discuss and analyze the results.Methods : According to CTPI and CT enhanced examination of tumor resection range, the patients who diagnosed as glioma parallel surgical treatment and postoperative pathology confirmed in January 2012- October 2014 in our hospital were divided into two groups:(1) CT enhancement(2) CT perfusion group, compared two groups in determining the scope of preoperative tumor area and the relapse rate of two sets of 1 month, 3 months, 6 months and 10 months after surgery.Results: 1.There are significant differences between preoperative CT enhanced tumor area and CT perfusion measurements measured(P < 0.05), the tumor area of CT perfusion is greater than that of CT enhancement. 2.There is no difference in recurrence rate between the two groups at 1 months and 3 months after operation(P>0.05). The recurrence rate of CT enhancement group in 6 months and 12 months after operation is significantly higher than that in CT group(P<0.05). There is no significant difference in the recurrence rate between the low grade glioma of two groups at the 1 month, 3 months, 6 months and 10 months after surgery(P>0.05). There is no significant difference between the high grade glioma of two groups at the 1 month and 3 months after surgery(P>0.05); The recurrence rate of high grade glioma of CT enhancement group in 6 months and 12 months after operation is significantly higher than that in CT perfusion group(P<0.05).Conclusions: The CT perfusion imaging can be more accurately than CT enhanced imaging to determine the scope of preoperative tumor. In the clinical course of treatment, the use of pre-perfusion imaging techniques to determine the scope of surgical resection can reduce the recurrence rate of patients with gliomas, especially to the high-grade gliomas after 6 months and 12 months having a good effect.