The Effect Of Propofol And Dexmedetomidineon Anesthetic Recovery In Obese Diabetic Patients Undergoing Gastric Bypass Surgery

Background:Currently, a lot of evidences showed that gastric bypass surgery can help achieve complete remission of T2 DM with obesity. And it might be a new treatment method for MS. But there is little research about the quality of such patients recovery.Aim:Tocomparethe advantages and disadvantages of propofol and Dexmedetomidine used for gastric bypass surgery in obese diabetic patients; Tocompare of The effect of propofol and Dexmedetomidine on anesthetic recovery in obese diabetic patients undergoing gastric bypass surgery.Methods:Sixty obese patients(body mass index35-40Kg/m2)were randomly assigned into three groups.Group A was Dexmedetomidine.Group B was propofol.Group C was propofol combined with Dexmedetomidine. All patients were operated with intravenous-inhalation general anesthesia. Recordedthe anesthesia time, time to extubation, orientation recovery time, VAS(Visual analogue pain score)in 24 hours. Record the untoward effects, such as vomiting, nausea, respiratory depression, and analgesic drug.Observed the incidence of adverse reactions.Result:No significantly differences ingeneral status and the surgery time(P>0.05) were found between the three groups. The extubation and orientation recovery times of group A were longer than the other two groups(P<0.05). The VAS sores of group B were higher than the other two groups(P<0.05). The extubation and orientation recovery times of group C were shorter than group A(P<0.05). The VAS sores of group C were lower than group B(P<0.05).ConclusionPropofol combined with Dexmedetomidine can inhibit the stress response, shorten the recovery time andreduce the anesthesia complications and improve the quality of recovery.