Maternal Efficacy Of Regular Oral Iron In Iron Deficiency Anemia In Pregnancy With The Risk Factors Of Postpartum Hemorrhage

Objective:To study the maternal efficacy of regular oral iron in iron deficiency anemia in pregnancy with the risk factors of postpartum hemorrhage.Methods:We retrospectively analysed the pregnant women with iron d-eficiency anemia with the risk factors of postpartum hemorrhage who acc-epted prenatal examination and delivered in January 2015-January 2016 in Guangxi Medical University First Affiliated Hospital (serum ferritin<20 ug/L(<6.5umol/L),hemoglobin<110g/L) in 67 cases,including 32 pregnant women of regular oral iron during pregnancy and after parturition,which c-ombined with twin pregnancy in 10 cases,marginal placenta previa in 6 c-ases,repregnancy with cesarean section in 8 cases,and mild preeclampsia i-n 8 cases,and 35 pregnant women of irregular oral iron during pregnancy and after parturition, which combined with twin pregnancy in 9 cases,ma-rginal placenta previa in 6 cases,repregnancy with cesarean section in 14 cases,and mild preeclampsia in 6 cases;took the 32 pregnant women of re-gular oral iron during pregnancy and after parturition as a treatment grou-p,and the 35 pregnant women of irregular oral iron during pregnancy and after parturition as a control group,made a detailed record of blood red protein,serum ferritin during pregnancy and after delivery,and 2 hours post-partum hemorrhage volume for the above two groups.Changes of hemogl-obin and serum ferritin levels in different periods of prenatal and postnata-1 period in two groups were analyzed by means of variance analysis.Pair-ed t test was used to compare the serum levels of hemoglobin, serum fer-ritin and 2 hours postpartum hemorrhage between the two groups.Results:Hemoglobin of the pregnant women with iron deficiency ane-mia with the risk factors of postpartum hemorrhage in early pregnancy,sec-ond trimester and late pregnancy and before delivery were 116.47±8.16g/ L,105.31±7.79g/L,99.88±7.20g/L,108.16±8.24g/L;serum ferritin were 41.26± 21.01ug/L,13.92±7.41ug/L,8.09±2.79ug/L,18.73±8.99ug/L.Compared to the s-econd trimester and late pregnancy,the hemoglobin and serum ferritin befo-re delivery were increased (p<0.05);2 hours postpartum hemorrhage of Va-ginal delivery was 241.11±136.99ml,2 hours postpartum hemorrhage of ce-sarean section was 352.17±207.52ml,the postpartum hemorrhage rate was 6.30%,postpartum hemoglobin and serum ferritin of delivery after forty-tw o days were 124.00±4.00g/L and 22.86±1.90ug/L respectively,which returne-d to normal levels(p<0.05).Conclusion:The oral iron in the pregnant women with iron deficiency anemia with the risk factors of postpartum hemorrhage makes prenatal serum ferritin and hemoglobin levels increase compared to the second trimester and the third trimester,postpartum serum ferritin and hemoglobin can be restored to normal levels,2 hours postpartum hemorrhage is not much,there is an important significance on the prevention of postpartum hemorrhage and the improvement of iron deficiencv anemia disease.