Clinical Observation Of In You Period In The Treatment Of Hypertension

Objective:To observe the effects of moxibustion on Yongquan acupoint in the perio d of the day from 5 p.m. to 7 p. m on perfection of high blood pressure leve Is, heart rate,antihypertensive effects and syndromes of TCM, and to prove that it has obviously advantage comparing with moxibustion on Yongquan acup oint not in the period of the day from 5 p.m. to 7 p. m, which not only dire ctly benefit hyperpietics, but also supply certain evidence for exploring t he method of safe and effective depressurization by chronomedicine combine d with non-pharmaceutical therapy furtherly.Methods:60 cases of patients with grade 1 hypertension were allocated into ther apy group, control group and blank group using nonrandomized controlled s tudy method, referring to "the guidelines for prevention and control of hyper tension" (2010 revised edition).Each group has 20 people.The moxibustion th erapy was given to therapy group in the period of everyday from 5 p.m. to 7 p. m(17-19 PM), and was lasted respectively on left and right Yongquan acup oint for 15min.6 times of therapy one week continuously for 4 weeks. Thera py need to be recorded everyday. The researchers reviewed observation index es and evaluated clinical effects for patients on the 2nd and 4th week of the rapy. The therapy time of moxibustion depend on patients’ will (except the period of of everyday from 5 p. m. to 7 p. m) in the control group. intervent ion program of moxibustion, treatment course and reviewing indexes were sam e as those in therapy group. The patients in the blank group were not arran ged any special therapy. The researchers followed the patients on the 2nd an d 4th week of therapy and recorded related indexes. After obtaining data, in tra-group comparison and comparison between groups were made in 3 groups b efore and after therapy, to evaluate the difference between them.Results:(1) Blood pressure comparison:intra-group comparison, comparing systol ic pressure and diastolic pressure before and after therapy among 3 groups, blood pressure drops are obvious in therapy group and control group before and after treatment, differences were statistically significant (P<0.01), bu t differences were not statistically significant (P>0.05) in the blank gro up before and after therapy; comparison among groups, comparing systolic pr essure and diastolic pressure before and after therapy among 3 groups, not o nly was the therapy group and control group more obvious than blank group, b ut also the therapy group was more obvious than control group,the analysis was statistically significant (P<0.01);the results of difference compariso n and comparison among groups are basically the same. (2) Heart rate compari son:intra-group comparison, comparing heart rates before and after therapy in the therapy group and control group, the decline of heart rate are obvio us in therapy group and control group before and after treatment (P<0.01), but There were no changes in the blank group before and after therapy (P>0. 05);Comparison among groups, differences were not statistically significant (P>0.05all) among three groups before and after therapy;difference compari son, compared with the blank group, the therapy group and control group can make the heart rate drops, but the difference between therapy group and con trol group is not obvious (P>0.05). (3) total scores of TCM symptoms comparis on:intra-group comparison, scores dropped obviously comparing with that be fore therapy both in the therapy group and in the control group (P<0.01), t here were no obvious changein the blank group before and after therapy (P>0. 05); comparison among groups, TCM symptoms total score in therapy group dr opped obviously after therapy,comparing with that of control group and blan k group(P<0.05, P<0.01), But the differences were not significant between blank group and control group(P>0.05);difference comparison, the difference s of TCM symptoms total score in therapy group and control group are more o bvious before and after therapy, comparing with that of blank group, but diff erence in therapy group is more outstanding than control group. (4)on the asp ect of depressurization effects and TCM clinical effects:the therapy in th e therapy group and in the control group all can reduce the blood pressure and improve TCM clinical symptoms effectively (P<0.01), and the therapy gr oup was more effective than control group, difference was statistically sig nificant (P<0.01). the differences of the curative effect were unconspicuou s among three groups, and less sample size may be the main reason.Conclusion:The moxibustion on Yongquan acupoint in the period of the day from 5 p. m. to 7 p.m can reduce patients’blood pressure and improve TCM clinical symptoms of patients effectively, and has obviously advantages comparing with that not in the period of the day from 5 p. m. to 7 p. m.