Multivariate Linear Correlation Analysis Of The Factors Influencing The Arterial Systolic Blood Pressure In Overweight And Obese Youth

[Objective] Analysis the factors influencing central systolic blood pressure in youth and to discuss the the role of serum levels of vitamin D and visfatin in the obesity related hypertension in youth by measuring of central systolic blood pressure(CSBP) and height、weight、vitamin D、visfatin in colleage students. [Method] According to the overweight and obesity standard develop by the Wo rld Health Organization, BMI ≥ 24 kg/m2 was defined as overweight, BMI≥ 28 kg/m2 was defined as obesity. Choose 108 cases as overweight and obesity group and 178 cases as control group. calculate the body mass index(BMI= weight/height2(kg/m2) by measuring the height, weight, Use a non-invasive Sphygmo Cor pulse analyzer to measure central systolic blood pressure, Using automatic analyzer to detect each biochemical values, Using enzyme-linked immunosorbent(ELISA) to detect serum vitamin D and visfatin levels within the young college students.First part: measurement of central systolic blood pressure, height, weight, blood biochemical and serum vitamin D and visfatin in young college students(286 cases), central aortic systolic pressure as dependent variable and index multi-ple linear regression analysis of the age, heart rate, body mass index, right arm circumference, CRP, vitamin D, visfatin, high density lipoprotein, low density lipoprotein, glycerin three fat, cholesterol, creatinine, urea nitrogen. To explore the risk factors of systolic blood pressure in youth.Second part: Compare the different of CRP、vitamin D and visfatin in overweight or obesity group and control group. Using Logistic regression analysis to explore the relationship between BMI and serum levels of vitamin D and visfatin. Then analysis the role of serum levels of vitamin D and visfatin in obesity related hypertension in youth.[Result]1.There is a linear correlation between youth center of systolic blood pre-ssure and body mass index(BMI), vitamin D, visfatin, CRP, triglycerides(cor-relation coefficient is 0.478、-0.116、0.120、0.172、0.106,P < 0.05,respectively).And BMI was a main factors which affecting central systolic pressure in youth.2. Serum vitamin D(121.19±47.75 vs 163.26±64.81)levels in Overweight and obesity group were lower than that in the control group(P < 0.01) and serum visfatin(266.10±77.29 vs 258.74±79.30) and CRP(3844.39±1585.25 vs 3248.94±1604.89)levels in overweight and obese group were higher than in controlgrou p(P>0.05). The serum the level of vitamin D(OR=0.059)、visfatin(OR=3.154)and CRP(OR=3.444) have a close relationship with BMI in the Logistic re-gression analysis(P<0.01).[Conclusion] 1.The factors which influencing central aortic systolic pressure in youth were BMI, CRP, vitamin D, visfatin and triglycerides,and BMI has a greatest impact on central aortic systolic pressure. 2.The serum levels of vitamin D,visfatin and CRP were closely related to BMI,which were involved in the occurrence and development of obesity related hypertension.