Clinical Outcome Assessment And Correlation Of Cellular Immune In Balgham-helit Type Vitiligo Patients

Objective: To The first task in Victoria Hospital vitiligo digital library based on the literature, according to "vitiligo Abnormal Humour classification criteria", concise clinical outcome assessment astringency phlegmatic type of vitiligo. Astringency phlegmatic again hospitalized vitiligo patients for the study, each tends to detect normal differentiation of regulatory T cells in peripheral blood and lesional tissue fluid T cell subsets in patients before and after treatment, and clinical outcome assessment vitiligo multivariate statistical analysis. To investigate the correlation between astringency phlegmatic vitiligo clinical outcome assessment in patients with cellular immune function. While the dimension pharmaceutical intervention into said cell immune regulatory mechanisms, compare before and after treatment comparison, look for vitiligo-dimensional medical intervention to improve healing and reduce the recurrence of new ideas.Method:(1) In accordance with "abnormal humoral medicine vitiligo dimensional classification criteria" for the previous cases were analyzed with a view to further concise astringency phlegmatic vitiligo main card(white) and a secondary certificate(pulse, tongue, the tongue, tongue, body, emotional, eye, urine and other variables indicators) and other clinical outcome assessment associated with the evaluation criteria.(2) to be hospitalized astringency phlegmatic vitiligo patients for the study, patients before and after their detection from peripheral blood CD4 + CD25 + regulatory T(Treg) cell levels and CD4 +, CD8 + T lymphocytes, and astringency phlegmatic multivariate analysis of clinical outcome assessment were vitiligo. Result:(1) CD4 + T lymphocytes, before treatment was 50.74% ± 9.62, and the control group(35.83 ± 0.52) comparing with a very significant difference, P <0.01; after treatment was 41.85 ± 8.40, after treatment compared with before treatment there are very significant differences, P <0.01, with a post-treatment control group(35.83 ± 0.52) significantly different contrast, P <0.05.(2) CD8 + T lymphocytes, before treatment was 47.54% ± 9.10, and the control group(55.42 ± 0.34) comparing with a very significant difference, P <0.01; after treatment was 57.15 ± 8.40, after treatment compared with before treatment there are very significant differences, P <0.01.(3) CD4 + CD8 + CD25 + T lymphocytes, before treatment was 5.66% ± 0.92, and the control group(3.34 ± 0.24) comparing with a very significant difference, P <0.01; after treatment was 3.11 ± 1.17, after treatment there are very significant differences, P <0.01 compared with before treatment.Conclusion:(1) Uighur medicine syndrome differentiation based on mature and remove abnormal mucus quality, blood circulation, metabolism and promote the formation of melanoma cells as the basic principles and take a mature and removal therapy, oral medication, topical medications and non-drug therapies comprehensive treatment therapy and other methods.(2) immune processes involved in the development and progression of vitiligo, and with Uighur medicine "kuwiti tabiiy"(Elemental) imbalance caused by vitiligo corresponding theory.(3) Uighur medicine comprehensive treatment CD4 + T, CD8 + T and CD4 + CD8 + CD25 + T lymphocytes also occurred significantly changed. Namely by disease activity and other factors, there is a big difference in the number and proportion of peripheral blood T lymphocyte subsets, is an important reason for the development and progression of vitiligo, for comprehensive medical treatment for this link Uighur undertaken lymphatic cell activation and other help to treat the disease, which requires further study.