Depression And Anxiety And Its Influeening Factors In Patients With Chronic Hepatitis B

Objective To describe the depressive disorder and anxiety disorder situation in patients with Chronic Hepatitis B; To analysze the relationship between the depressive disorder and anxiety disorder and the socio-demographic variables, illness perception,perceived social support, and alexithymia. In order to provide the basis and reference for the psychological treatment of patients with Chronic Hepatitis B.Methods: Participants in this study were recruited from the department of infectious deisease in the first Affiliated hospital of Anhui Medical University from Sep. 2014 to Feb. 2015. A face to face questionnaire investigation was conducted by using Depression Rating Scale( SDS), Self-Rating Anxiety Scale( SAS), socio-demographic questionnaire, Illness Perception Questionnaire Revised( IPQ-R), Perceived Social Support Scale( PSSS), and Chinese version of Toronto Alexithymia Scale( TAS-20).Data are presented as means± standard deviations to understand the depressive disorder and anxiety disorder situation. Two independent sample t-test and analysis of variance( ANOVA) were used to analyze the relationship between socio-demographic variables and deprseeion and anxiety. Pearson’s correlations was performed to analyze the relationships between the scores of SAS, SDS and IPQ-R, PSSS, and TAS-20. All p data reported used two-tailed significance and p < 0.05 was the criterion for significance.Statistic analyses were conducted with the SPSS version 10.0(Chicago, IL, USA).Results: The number of patients without depression was 89(67.4%), mild was37(28.0%), moderate was 5(3.8%), and severe was 1(0.8%). The number of patients without anxiety was 100(75.8%), mild was 25(18.9%), moderate was 5(3.8%), and severe was 2(1.5%). The number of patients with two was 19(14.4%).There is no significant difference in the degree of deperession in different gender,age, marital status, education level, and health burden. Medical burden was significantly associated with depression. All socio-demographic factors had no significant difference with the degree of anxiety.Pearson’s correlations showed positive significant associations between depression and Consequences and Illness coherence, and negative significant associations with Personal control and Treatment control(P< 0.05). The degree of anxiety was significant associated with Consequences, llness coherence and Emotional representations positively, and significant associated with Personal control and Treatment control negatively(P< 0.05).Perception support out of family and perception support from family were significantly and negatively associated with depression and anxiety. Difficulty identifying feelings, difficulty describing feelings to others, and externally-oriented thinking were significantly and positively associated with depression and anxiety.Conclusion There is a certain incidence of depression and anxiety. The patients who fetl heavy medical burden has the more depression than those who felt mild. Patients have different scores of depression and anxiety when they felt different illness perception. Perceived social support was negatively and significantly with depression and anxiety, but alexithymia was positively and significantly with them. Psychological factors played an important role in the development of depression and anxiety.