Case-Control Study On Children With Allergic Rhinitis And Obstructive Sleep Apnea-Hypopnea Syndrome Treated By Surgery Combined Sublingual Innunotherapy Administering

Background obstructive sleep apnea hypopnea syndrome(OSAHS) is due to upper airway partial or complete obstruction,causing a decline in the quality of sleep,secondary to multiple system damage disease syndrome.Of all ages are possible,and the illness have different degree.Children are in the important period of growth and development,so the impact of the OSAHS for children is more far-reaching.It can result in children with poor growth and development,the decrease of the pulmonary cardiac function, hearing is affected, such as tinnitus, ear fullness, hearing decline, etc.,adenoid face and other serious complications.With the prevalence of OSAHS in children, the attention of parents and clinicians is gradually being attracted.Most of the domestic research are focus on the improvement of surgical methods. his study is inspired by the postoperative recurrence of symptoms in some children,Snoring children with allergic rhinitis were given surgery combined with sublingual immunotherapy(SLIT).Objective Snoring children with allergic rhinitis were treated with surgery combined with sublingual immunotherapy(SLIT) or with simple surgery,by comparing the clinical curative effect to investigate the influencei of SLIT on the postoperative symptoms of sleep apnea children,with allergic rhinitis.Method 60 cases with allergic rhinitis and sleep apnea were selected from January2012 to April 2014,results of all dust mite skin prick test were "+ + +" or”++++”,who werer andomly divided into two groups, experimental group(30 cases) and control group(30 cases), the experimental group was treated with the surgery and SLIT 1month after the surgery(30 cases), the control group was treated with simple surgery(30 cases),.Surgery was bilateral tonsillectomy and adenoidectomy.Using the OSA-18 and TNSS volume table scored sleep snoring symptoms(sleep apnea, mouth breathing.apnea, repeated awakeningetc.) and nasal symptoms(stuffy nose, sneezing,nasal itching, runny nose),respectively before operation and 1 month. 7 months. 13 months.19 months after operation in two groups of children.Using the statistical method, we compared the differences between the two groups and the score of the patients within each group before and after treatment.Result Scores of sleep snoring symptoms and nasal symptoms before treatment in the two groups of children were compared, and the differences were not statistically significant(P > 0.05); after 1 month of surgical treatment, scores of snoring symptoms and nasal symptoms in the two groups were significantly lower, and the difference was statistically significant(P < 0.05); For the experimental group of children,scores of snoring and nasal symptoms were significantly decreased 6 months and 12 months after SLIT;13 months and 19 months after SLIT,there is no obvious difference; For the control group, scores of snoring symptoms and nasal symptoms were obviously higher7 months. 13 months and 19 months after operation compared to that of 1 month after operation.Conclusion Surgery combined with SLIT treatment can significantly improve the symptoms of snoring and allergic rhinitis in children, increase the effect of surgery, and reduce postoperative recurrence.