Rabbit Femoral Artery Thrombosis After Thrombolysis In Researches On The Change Of Function Of Blood Vessel Elasticity

Objective: application of ultrasonic echo tracking technology and strain technology evaluation of thrombosis and thrombolysis different conditions after unilateral rabbit femoral artery thrombosis in blood vessel elasticity function changes in the characteristics,pathologic microcirculation and embolism after thrombolysis in detecting is a standard,explore thrombosis in blood vessel elasticity function change characteristics indicated significance of microcirculation and embolism.Methods: 72 New Zealand white rabbit,successfully make thrombosis model, targeted microbubble carrying urokinase under low frequency ultrasound assisted irradiation conditions thrombolysis, application of ultrasonic technology in different conditions before and after the formation of thrombus and thrombolysis measurement after unilateral femoral artery thromosis in blood vessel elasticity parameters.Made of calf muscle pathological detection, distal tissue microcirculation embolism.Results: ? after targeted microbubble carrying urokinase thrombolysis, not tong group, part of thbe accommodation, complete accommodation on the number of rabbits respectively, 23, 26, 32. ? Thrombosis after blood clots in the arteries of alpha, beta, PWV before a thrombosis increased(P < 0.05), the arterial DC, CC,RS, RSR is thrombosis has reduced significantly(P < 0.05).?Different conditions after thrombolysis treatment, complete accommodation artery DC less tong group and part of financing group increased(P<0.05) or less;Artery CC to completely accommodation is part of the accommodation group increased(P< 0.05) or less;Longtop group artery alpha,beta, completely PWV less tong group and part of the accommodation are reduced, are statistically significant(P <0.05) or less.(4)after distal tissue microcirculation and bolt less blood clots in arteries embolization group increased PWV, and statistically significant(F =4.4899, P < 0.05).Conclusion: thrombosis thrombosis after the recent increase in arterial stiffness, elasticity hypofunction.Thrombolysis effect directly affect the elasticity of the thrombosis in blood vessel function, distal tissue microcirculation and embolism can causeblood clots in arteries is given priority to with pulse wave conduction velocity of elastic function decline, the evaluation of the PWV blood microcirculation and embolism has a certain significance.