| Objective:A comparative study on elderly patients of therapeutic safety and efficacy of laparoscopic partial nephrectomy(LPN) with traditional open partial nephrectomy(OPN) in localized renal cell carcinoma.Methods:It is a retrospective analysis of the local renal carcinoma patients from September 2013 to March 2015 our department treated, the age range between 62 to 83 years, with a median age of 69.3 years, all cases underwent partial nephrectomy. Laparoscopic group was the experimental one, made up of 30 patients, while the traditional open group was a control one, constituted of 16 patients. Statistics were experimental group and control group for age, sex, location of the diseased kidney, tumor location, tumor size, operative time, blood loss, postoperative drainage,intraoperative warm ischemia time, postoperative gastrointestinal recovery time, glomerular filtration rate(GFR) before and after surgery of the diseased kidney, changes in length of hospital stay and postoperative serum creatinine levels, cancer positive margin rate before and after surgery, postoperative hospital stay, incidence of complications.Results:There had no diffenences between the two groups in age, sex,location of the diseased kidney, tumor location, tumor size, glomerular filtration rate(GFR) before and after surgery of the diseased kidney,changes in length of hospital stay and postoperative serum creatinine levels, cancer positive margin rate before and after surgery, complication rate after surgery(p> 0.05); The operative time, blood loss, postoperative drainage, postoperative gastrointestinal recovery time, postoperative hospital stay in the experimental group were better than those of the control group(p <0.05); The intraoperative blood warm ischemia time in control group was better than that of the experimental group(p <0.05).Conclusion:For the localized renal cell carcinoma in elderly patients, although open partial nephrectomy is superior to laparoscopic surgery in terms of warm ischemia time, laparoscopic partial nephrectomy has a shorter operative time and a faster postoperative recovery.At the same time, it is less invasive, safe and effective that should be promoted in the elderly population. |