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Assessment Of The Right Ventricular Function In Patients With COPD Using MSCT

Posted on:2017-02-11Degree:MasterType:Thesis
Country:ChinaCandidate:L TangFull Text:PDF
GTID:2284330482978250Subject:Medical Imaging and Nuclear Medicine
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Objective: To investigate the MSCT for chronic obstructive pulmonary disease(COPD) patients with right ventricular function assessed value, and real-time three-dimensional echocardiography(RT-3DE) findings.Methods: 32 patients with clinical and pulmonary function tests prove row MSCT cardiac patients with COPD enhanced scanning, image reconstruction combined with heart and cardiac function analysis software,get COPD patients with right ventricular function parameters: right ventricular end diastolic volume(RVEDV), right ventricular end-systolic volume(RVESV), right ventricular stroke volume(RVSV) and right ventricular ejection fraction(RVEF), and MSCT result and the corresponding parameters measured by RT-3DE measured by paired t test.Results:(1)MSCT measured RVEDV, RVESV, RVSV and RVEF value was 126.4±12.1ml, 66.7±10.4ml, 57.6±9.5ml and 44.7±6.8%;(2) RT-3DE corresponding measured values were 117.1±11.3ml, 58.9 ±9.1ml, 62.3±8.2ml and 48.2±7.1%;(3)MSCT the measured values in RVEDV and RVESV than RT-3DE measured value is slightly higher, RVSV and RVEF slightly lower than the RT-3DE, but measured by the two methods The results have a good correlation(r followed 0.863,0.841,0.875 and 0.856, all P >0.05).Conclusion: MSCT can accurately and quickly provide COPD patientswith right heart anatomical and functional information for the clinic.Objective: To investigate the use of MSCT evaluation of chronic obstructive pulmonary disease(COPD) patients with right ventricular function parameters and pulmonary function tests(FPT) relevant results.Methods: In accordance with the 2011 version of "COPD diagnosis,treatment and prevention of the global strategy" in lung function grading standards, the patients with the clinical diagnosis of COPD and pulmonary function tests in 39 cases, according to the results of pulmonary function test group divided into eight patients with mild, moderate 12 cases of group, 14 cases of severe group, five cases of very severe group, and collected in the same period by clinical and radiological examination without significant cardiopulmonary disease 18 cases of healthy volunteers. For COPD group and control group underwent heart MSCT enhanced examination, and record the relevant right ventricular function and morphological indicators, including end-diastolic volume(RVEDV), end-systolic volume(RVESV), stroke volume(RVSV), right ventricular shot ejection fraction(RVEF), right ventricular mass(RVMM) and right ventricular free wall thickness(RVFW),the results andx± s representation. COPD group and control group for each group of data-line single-factor analysis of variance, correlation analysis of the COPD group RVEF, RVMM and RVFW and pulmonary function(PFT)Check parameter row Spearman.Results: Control and COPD groups RVEDV were:(143.4 ± 11.9),(140.2 ± 8.5),(132.5 ± 9.1),(113.4 ± 8.8),(122.3 ± 11.3) ml; RVESV respectively:(68.4 ± 5.6),(67.6 ± 4.8),(66.1 ± 4.4),(64.2 ± 5.0),(76.4 ± 8.4)ml; RVSV respectively:(73.1 ± 10.5),(69.2 ± 4.5),(65.8 ± 5.1),(45.1 ± 4.2),(40.8 ± 3.6) ml; RVEF respectively:(52.4 ± 1.9),(50.7 ± 2.1),(49.5 ± 1.9),(38.7 ± 3.3),(32.2 ± 3.1)%; RVMM are as follows:(39.7 ± 3.5),(42.9 ± 2.5),(47.5 ± 2.9),(50.8 ± 2.4),(56.5 ± 2.3) g; RVFW respectively:(3.22 ± 0.42),(3.41 ± 0.37),(4.33 ± 0.73),(5.02 ± 0.76),(5.78 ± 0.43) mm. RVEDV in the control group and mild group, the moderate group was not statistically significant in the control group and severe group, the very severe group was statistically significant; RVESV in the control group and mild group, the moderate group was not statistically meaning, in the control group and severe group, the very severe group was statistically significant; RVSV between the control group and mild group was not statistically significant, between the control group and the moderate group, severe and very severe group was statistically significance; RVEF in the control group and mild group,moderate group was not statistically significant between in the control group and severe group, the very severe group was statistically significant, RVEF and FEV1, FEV1/FVC% correlation coefficients were 0.826 and 0.797, both P <0.05; RVMM between the control group and mild group had no statistical significance between the control group and the moderate group, severe and very severe group was statistically significant, RVMM and FEV1,FEV1/FVC% correlation coefficients were-0.821 and-0.783, both P <0.05;RVFW between the control group and mild group had no statistical significance between the control group and the moderate group and severe group and very severe group statistically significant, RVFW and FEV1,FEV1/FVC% correlation coefficients were-0.809 and-0.745, both P <0.05.Conclusion: Right ventricular mass and right ventricular free wall thickness measurement MSCT with exacerbation of COPD severity increases,and treated as early changes in right ventricular remodeling; right ventricular ejection fraction and pulmonary function in patients with COPD classified as negative, and in severe, very severe decline of mild to moderate significantly.
Keywords/Search Tags:Pulmonary disease,chronic obstructive, Ventricular function,right, Tomography,X-ray computed, Echocardiography, three-dimensional, pulmonary function tests
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