Clinically Ovservation With Wen Shen Tiao Gan Prescription Combined With Clomiphene Treatmen Kidney Deficiency Liver Depression Type Of Anovulatory Infertility

ObjetiverThis study aims at observation of decoction of warming the kidney and regulating the liver with clinical curative effect of clomiphene citrate in the treatment of kidney deficiency and stagnation of Qi due to depression of the liver of anovulatory infertility, and to explore its mechanism.Objective evaluation of traditional Chinese medicine and Western medicine combined with the clinical efficacy of therapy of the disease, in order to make up for the defect of high clomiphene citrate ovulation rate, low pregnancy rate, shorten the treatment time, to provide security for the treatment of kidney deficiency and liver qi stagnation type ovulatory disorder infertility, exact, effective treatment method.Methods:Standard of the kidney deficiency and liver qi stagnation type ovulatory disorder infertility patients 60 cases met the inclusion are selected randomly divided into the treatment group and control group according to the ratio of 1:1, each with 30 cases in each.In treatment group were treated with Decoction of warming the kidney and regulating the liver one dose daily. Two minutes morning and evening service, at the same time in the menstrual cycle, 5 days or the use of progesterone withdrawal bleeding in 5 days of oral administration clomiphene citrate tablets (each tablet 50mg, high special Pharmaceutical Co., Ltd., Cyprus), once a day,50mg/times, and even served 5 days; the contrast group only treated with clomiphene and specific way of taking the same as the treatment group.The two groups of patients were treated with 1-2 treatment, February was 1 course of treatment. After the end of treatment, the observed warming the kidney and regulating liver soup with clomiphene citrate and simple use of clomiphene citrate on kidney deficiency and liver qi stagnation type ovulatory disorder infertility clinical synthesis curative effect, TCM symptoms integral, the curative effect of TCM symptoms, basal body temperature, dominant follicle diameter, ovulation, endometrial thickness, ovulation rate, pregnancy rate and embryo loss rate.Results:Two use the statistical analysis of the clinical effect of two groups of patients after the show, between the two groups compared with statistical significance (P< 0.05), the treatment group than the control group; in pregnancy rate, the ovulation rate, the TCM symptoms integral, the curative effect of TCM symptoms, BBT improve, endometrial thickness, the treatment group was better than the control group (P< 0.05); in the dominant follicle diameter, between the two groups no significant difference (P> 0.05); treatment group embryo loss rate was 7.14%, control group embryo loss rate was 16.6%, P< 0.05. The rate of embryo loss in the control group was higher than that in the treatment group, but it was not statistically significant because of the number of clinical observation, and the need for further observation and study. Group patients were treated with 1-2 treatment, February for 1 courses. After the end of treatment, the observed warming the kidney and regulating liver soup with clomiphene citrate and simple use of clomiphene citrate on kidney deficiency and liver qi stagnation type ovulatory disorder infertility clinical synthesis curative effect, TCM symptoms integral, the curative effect of TCM symptoms, basal body temperature, dominant follicle diameter, ovulation, endometrial thickness, ovulation rate, pregnancy rate and embryo loss rate.Conclusion:With Decoction of warming the kidney and regulating the liver CC treatment of kidney deficiency and liver qi stagnation type ovulatory disorder infertility treatment is obviously superior to the single use CC, can improve the ovulation rate, pregnancy rate, at the same time, but also comprehensive improvement of the symptoms of kidney deficiency and liver qi stagnation, improve ovulation, endometrial thickness to be ready for the implantation of a fertilized ovum and after pregnancy can also maintain effect on pregnancy, for the treatment of kidney deficiency and liver qi stagnation type ovulatory disorder infertility to provide a safe, exact and effective drugs, and is worthy of promotion and use.