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Effect Of B Hemolytic Streptococcus Infection On Maternal And Neonatal Outcomes In Late Pregnancy

Posted on:2016-06-13Degree:MasterType:Thesis
Country:ChinaCandidate:D Y XuFull Text:PDF
GTID:2284330482977374Subject:Obstetrics and gynecology
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BackgroundStreptococcus is a gram positive, mainly divided into alpha, beta, gamma three types, beta streptococcus (hemolytic streptococcus) is divided into A and B group hemolytic streptococcus (B) is mainly planted in the urinary tract, lower digestive tract and infant’s upper respiratory tract, the role is more obvious. Studies have shown that Chinese women during pregnancy, GBS carrier rate between 8.3%,11.8%, in intrauterine infection or delivery of GBS easily by maternal transmitted directly to the fetus or newborn. At present, it has become one of the main pathogens of severe neonatal infections. GBS mainly influence on pregnant women:cause premature rupture of fetal membranes, premature birth, amniotic cavity infection, puerperal infection, puerperal sepsis, caused by other obstetric complications. But there are also studies have shown that GBS infection in preterm and full term pregnant women were not statistically significant, so the GBS infection and can not be used as a direct factor in premature and premature rupture of membranes. In GBS and cesarean section rate, puerperal infection, forceps delivery rate between the relationship is not very clear, in order to further prove the GBS infection in late trimester of pregnancy on maternal and neonatal outcomes of influence, so this research is necessary.ObjectiveRetrospective analysis of infection of type B hemolytic streptococcus in pregnant women during 36 weeks-38 weeks, study the GBS infection in late trimester of pregnancy on maternal and neonatal outcomes of influence.MethodsThis paper in January 2015-June 2015 in our hospital for check of 268 cases of pregnant women were selected. The standard of entry into the group of women:(1) all of the pregnant women in the early pregnancy were confirmed and checked by early B ultrasound examination; (2) singleton; (3) all patients did not use antibiotic s in the lmonth.Excluding patients with systemic disease, pregnant 36 weeks-38 weeks in the vagina 1/3 and anus weeks sampling and bacterial culture. GBS positive and GBS negative, Retrospective analysis of 2 groups is intrapartum and postpartum data such as pregnant women with cesarean section rate, puerperal infection, forceps delivery rate, fetal distress, postpartum hemorrhage, neonatal jaundice, neonatal asphyxia.Data using SPSS software system, the measurement data with (x±s) to represent and between groups using student’s t test; count data between groups by chi square test, P< 0.05 for the difference is statistically significant, then the results of analysis, draw the conclusion.Result(1) 268 cases of pregnant women testing GBS positive 42 cases, accounting for 15.67%; 226 cases of GBS negative pregnant women, accounting for 84.33%; the positive rate of GBS in pregnant women aged ≥35 years was 11.57%(31/268), was significantly greater than the age<35 pregnant women GBS positive rate of [4.10%(11/268)], P<0.01; the positive rate of GBS>2 the number of abortion of pregnant women 10.45% times (28/268), significantly higher than the number of abortions less than or equal to 2 times the positive rate of pregnant women GBS [5.22%(14/268)], P<0.05; the positive rate of GBS in pregnant women was 8.96% times>1 times (24/268), the positive rate of GBS in pregnant women following high school education was 8.58%(23/268), and the production is 1 times the positive rate of pregnant women GBS [6.72%(18/268)], high school and higher education of pregnant women GBS positive rate of [7.09%(19/268)], P>0.05.(2) GBS positive group, premature rupture of membranes in 8 cases (19.05%),9 (21.43%) cases of amniotic fluid turbidity, the incidence rate was significantly higher than GBS negative group [Prom 14 (6.19% cases), amniotic fluid turbidity 15 (6.64%)], P<0.05; GBS positive group 6 (14.29%) cases of puerperal infection, fever 4 (9.52% cases), and GBS negative groups [51 (22.57%) cases of puerperal infection, fever in 28 cases (12.39%)], P>0.05; GBS positive group in cesarean section in 7 cases (16.67%), was significantly higher than GBS negative group [14 (6.19% cases), P<0.05 group; excluding two cases of cesarean section after the GBS positive group,5 cases of fetal distress (14.29%), was significantly higher than GBS negative group [10 (4.72% cases), P<0.05; GBS positive group of postpartum hemorrhage, forceps delivery rate and GBS negative group, P>0.05.(3) In GBS positive group, Neonatal pneumonia 4 cases (11.43%), Fetal asphyxia 6 cases (17.14%), Pathological jaundice 4 cases (11.43%); Compared with negative group Pneumonia 6 cases (2.83%), Fetal asphyxia 12 cases (5.66%), Pathological jaundice 6 cases (2.83%),, significant differences. P<0.05.。ConclusionAged≥35 years, the risk factors of vaginal GBS positive in pregnant women, the positive rate of vaginal GBS positive can increase the incidence of premature rupture of membranes and amniotic fluid, increase the incidence of neonatal infection, cesarean section rate and incidence of jaundice and fetal distress.
Keywords/Search Tags:late pregnancy, B type hemolytic streptococcus, puerperal infection, neonatal pneumonia
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