| Objective:Through study on epidemiological survey and analysis of brucellosis clinic population in Songyuan City of Jilin Province,got to know the treatment and infection of brucellosis clinic population, reveal epidemiological characteristics of different infected people, and discuss the influence factors of symptomatic infection, asymptomatic infection and suspected infection. The results of the study provide scientific basis for the brucellosis prevention and population-based intervention. Methods:In the study, information about brucellosis clinic population in Songyuan City CDC from On January 1, 2009 to December 31, 2012 were collected, including general condition, medical history, culture of livestock raising, contacting history, family history of infection, clinical manifestations, diagnosis and so on. SPSS 19.0 and SAS9.1.3 software were used for statistical analysis. Descriptive statistical analysis was carried out on the distribution of different groups. Chi-square test was used in the univariate analysis of the influence factors for brucellosis infection, and Multinomial Logistic was used in the multivariate analysis. Results:1. In the 3557 cases of brucellosis clinic population, 991 cases(27.86%) were diagnosed with symptomatic infection, 169 cases(4.75%) were diagnosed with asymptomatic infection, 382 cases(10.74%) were diagnosed with suspected infection, and 2015 cases(56.65%) were negative.2. In different brucellosis clinic population, the number of cases of men was more than that of women. The sex ratio of the symptomatic infection, the asymptomatic infection, the suspected infection and the negative was 3.27:1, 2.93:1, 2.50:1, 1.49:1. The age distribution of the different clinic population: The median and interquartile in the symptomatic infection was 43(34~52), which in the negative was 41(30~51), and the Mean ± standard deviation in the asymptomatic infection was 40.43±13.50, which in the suspected infection was 42.77±12.30. In different brucellosis clinic population, the Han had the greatest number, more education at the primary level, and the major occupation were farmers and herdsmen. The difference of crowd-constitute ratio of the symptomatic infection, the asymptomatic infection, the suspected infection and the negative between different sex, age, culture level, occupation showed statistical significance( X~2=94.917,P < 0.001; X~2=73.112,P < 0.001;P=0.005; X~2=122.453,P <0.001).3. There was the highest incidence of the clinical symptom of fever, which accounted for 73.86%, 65.97%, 40.25%, followed by asthenia, hyperhidrosis, joint pains in the symptomatic infection, the asymptomatic infection and the suspected infection. The clinical sign with the highest incidence was testicular swelling(4.24%, 3.66%, 1.54%).4. In different brucellosis clinic population, people in symptomatic infection or asymptomatic infection had higher rate of sheep raising(65.99%, 71.01%), followed by cattle raising, pig raising, dog raising, and the rate of deer raising was lowest. The difference of crowd-constitute ratio of the symptomatic infection, the asymptomatic infection, the suspected infection and the negative between people keeping sheep, cattle, pig, dog and not doing this showed statistical significance( X~2=78.879,P <0.001;X~2=16.825,P=0.001;X~2=20.753,P<0.001;X~2=11.617,P=0.009).5. Different brucellosis clinic population had higher contact rate of apoblema and fur, followed by dust and faeces, and the contact rate of dairy-meat was lowest. The difference of crowd-constitute ratio of the symptomatic infection, the asymptomatic infection, the suspected infection and the negative between people contacting apoblema, fur, faeces, dust and not doing this showed statistical significance(X~2=216.086, P<0.001; X~2=54.419, P < 0.001; X~2=87.182, P < 0.001; X~2=22.603, P < 0.001).The difference of crowd-constitute ratio of the symptomatic infection, the asymptomatic infection, the suspected infection and the negative between people contacting with risk factors through the skin and respiratory tract infections and no contact showed statistical significance(X~2=172.407, P<0.001; X~2=21.730, P<0.001).6. In the 3557 cases of brucellosis clinic population, 431 families were found in which at least one person was infected with brucellosis. 102(23.67%) members were symptomatic infected with brucellosis, 18(4.18%)member cases were asymptomatic infected, 36(8.35%) member cases were suspected infected, and 275(63.81%) member cases were negative.The difference of crowd-constitute ratio of the symptomatic infection, the asymptomatic infection, the suspected infection and the negative between people whose family member being infected and being healthy( X~2=10.473, P=0.015).7. Through multi-factor analysis showed that the influence factors for symptomatic infection were sex, age, occupation, contacting with apoblema, fur and dust; the influence factors for asymptomatic infection were sex, contacting with apoblema and fur; the influence factors for suspected infection were sex, occupation, contacting with apoblema, fur, faeces. Conclusions:1. From 2009 to 2012, there were 991 cases of the symptomatic infection, 169 cases of the asymptomatic infection and 382 cases of the suspected infection in brucellosis clinic population, constituent ratio accounted for 27.86%, 4.75%,10.74%.2. In the symptomatic infection, the asymptomatic infection and the suspected infection, the number of cases of men was more than that of women. Of all the people, young and middle-aged group were in the majority, primary school education were in the majority. Farmers and herdsmen were of main groups.3. There was a higher incidence of the clinical symptom of fever, asthenia, hyperhidrosis, joint pains, as so as a higher incidence of the clinical sign of testicular swelling in the symptomatic infection.4. The common risk factors for brucellosis symptomatic infection, asymptomatic infection and suspected infection were male, contacting with apoblem and fur; The common risk factor for brucellosis symptomatic infection and suspected infection was farmers and herdsmen; 26~65 years old and contacting with dust were independent risk factors for brucellosis symptomatic infection; Contacting with faeces was independent risk factor for brucellosis suspected infection. |
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