Prognostic Factors In Status Epilepticus And Prognosis Evaluation

Objective:To analyze the prognosis factors in status epilepticus and confirm the external validity of the Status Epilepticus Severity S-core (STESS) prediction functions for outcome in patients with status epilepticus.Methods:Retrospectively, collect prognosis factors in status epil epticus of 50 patients. These factors include gender,age, SE aetiology, seizure type at SE onset, history of prior seizures or epilepsy, level of consciousness, duration of SE, albumin and infection. Using STES-S score to evaluate the prognosis of patients, then evaluate the effec-tiveness of the STESS score.Results:1. Single factor analysis:age, history of prior seizures or epileps-y, level of consciousness and infection were prognosis factors in sta-tus epilepticus(P<0.05).Gender,SE aetiology,seizure type at SE onset a-nd albumin were not prognosis factors(P>0.05). Multiple multivariable logistic regression models selected two factors:duration of SE(OR3.6 45),level of consciousness (OR2.877)2.28 status epilepticus patient in the STESS 0-2 group were all alive.10 status epilepticus patient in the STESS 3-6 group were died (45.4%),12 patient were alive(54.6%).There was significant difference among the prognostic of patienst in different group(P<0.01).The recei ver operating characteristic curve for prediction of death by the Stat-us Epilepticus Severity Score had an area under the curve of 0.92. The optimal cutoff point is 3.Conclusion:Age, history of prior seizures or epilepsy, level of consciousness, duration of SE and infection were prognosis factors in status epilepticus. Level of consciousness and duration of SE are the direct related factors of the prognosis of status epilepticus. Status Ep-ilepticus Severity Score performed reasonably well on our patients w-ith status epilepticus. The optimal cutoff point is 3.