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The Meaning Of Hip Strength Analysis In The Prediction Of Osteoporotic Hip Fractures

Posted on:2016-12-08Degree:MasterType:Thesis
Country:ChinaCandidate:X J RenFull Text:PDF
GTID:2284330479995704Subject:Imaging and nuclear medicine
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Objective : To evaluate the changing of the geometric structure of the hip in post-menopausal females,to study its value in predicting osteoporotic hip fractures.Material and methods:216 post-menopausal females were examined by dual energy X-ray absorptiometry(DXA),the conventional densitometry were measured,geometric structure also were analysised using Hip strength analysis(HSA) program, including section modulus(SEM),Cross-sectional moment of inertia(CSMI),Cross-sectional area(CSA),,buckling ratio(BR), cortical thickness of femoral neck(FNCT)、Neck shaft angle(NSA).They were divided into fracture group and normal group by whether fracture,were divided into normal group,low bone mass and bone osteoporosis group.Those datas were statistical analysised.Results:①BMI,FN-BMD,CSA,CSMI,FNCT,SEM were significantly lower and age,BR were higher in the fracture group compared with controls.②The logistic regression analysis confirmed that FN-BMD,FNCT were the more important risk factors of hip fracture incidence.③FN-BMD,CSA,CSMI,FNCT,SEM were positively correlated with age, FN-BMD CSA,SEM were significantly positively correlated with FN-BMD( r = 0.945,r =0.763,P < 0. 001),BR was negatively correlated with FN-BMD( r =-0.854, P < 0. 001)and age,NSA°was not correlated with FN-BMD and age.④The fracture discrimination ROC curve for the logistic regression probability model incorporating the geometric parameters of the hip and FN-BMD was significantly larger than any other groups for T-score alone(0.860,P=0.000).Conelusion:1.The hip strength of post-menopausal females is not only influenced by bone loss,but also by the changed of its hip geometric structure,both of them were the riskes of hip fractures in post-menopausal females.2.Combining with FN-BMD and hip geometric structure, may have a more effective capability of predicting hip fractures.
Keywords/Search Tags:Bone mineral density, Dual energy X-ray absorptiometry(DXA), Hip strength analysis(HSA)
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