The Pulmonary Function Test And Relationship Of Wheezing Diseases In Infants And Mycoplasma Pneumonia Infection

Objective:To understand the relationship between infant wheezing illness and Mycoplasma pneumoniae infection and see variation of pulmonary function of ininfants asthmatic disease with Mycoplasma pneumonia by comparing the results of pulmonary function tests, in order to reduce the incidence of wheezing and help clinical early diagnosis and treatment.Methods : 0-3 old inpatient of asthmatic disease(bronchiolitis, asthmatic bronchitis, infantile asthma, pneumonia) patients 185 cases were detected MP-Ig M in January 2014- December 2014 Zunyi Medical College Hospital pediatric by application of passive particle agglutination method.The mycoplasma pneumonia were divided into infection group, negativemycoplasma pneumonia were divided into non infection group, and the infection group and non infection group were followed up the clinical and pulmonary function tests with Half a year. Through the t test, chi square test between the infection group and the non infection group were compared with lung function index and clinical data,and analyze its clinical significance.Results:1. Infection and non-infected group asthmatic disease patients children in stable condition after one week of pulmonary function test results comparisons are statistically significant(P <0.05), in which Ratio of TPTEF to total expiratory time and Ratio of VPEF to total expiratory volume compare with a statistically significant(P <0.01); 2. Infected and non-infected group regardless of severity with comparison of Ratio of TPTEF to total expiratory time and Ratio of VPEF to total expiratory volume were statistically significant(P <0.05), Their lung function of respite <3 d And wheezing < 3 times based with mild injury; Their lung function of respite> 3 d and wheezing> 3 times based with moderate to severe damage. 3.33 cases of infection had 14 patients who developed infantile asthma,and the rate was 42.42%; 53 cases of non-infection group had 6 patients who developed infantile asthma, and the rate was 11.54%,the two groups was statistically significant(P <0.05). 4. Patients of infected group had changed asthma that the heredodiathesis and atopy were detected in 64.28%,without regular antimycoplasma pneumonia therapy in 28.57%,other infection in 7.15%.5.Follow-up six months later infection group and non-infected group with comparison of wheezing relapse frequency, Whether cough cure are statistically significant(P <0.05). The infected and non-infected group the efficacy of corticosteroids was not statistically significant(P>0.05). 6. Follow-up in June after infection by the formal treatment of pulmonary function changes and changes in lung function without regular treatment was statistically significant(P<0.05).Conclusion:This study shows that Mycoplasma pneumoniae infection can cause changes of lung function of asthmatic disease, one important indicator of the onset of asthmatic disease in children is Ratio of TPTEF to total expiratory time and Ratio of VPEF to total expiratory volume, severe illness of lung function in severe damage to the main, the mild to mild injury based; mycoplasma pneumoniae infection in asthmatic disease development process of asthma may have a certain impact,meanwhile there were other factors may play a part in it.Mycoplasma pneumoniae infection may increase frequency of wheezing and cause which coughing is difficult to cure.by making regular anti pneumonia mycoplasma treatment of lung function recovery compared with without formal treatment is quickly. Therefore, we should be paid to check lung function measurement and Mycoplasma pneumoniae, so early detection, early diagnosis, early treatment and reduce the incidence of asthma.