The Clinical And Pathological Data Analysis Of Differentiated Thyroid Carcinoma

Objective: To analyze large green Affiliated with differentiated thyroid carcinoma(DTC) patients with clinical data through retrospective study, analysis and diagnosis of the disease, treatment and prognosis for future clinical diagnosis of DTC to provide valuable clinical data basis.Methods: Affiliated Hospital of Qinghai University breast surgery treated and diagnosed during January 1, 2011--2014 on October 31 four years in patients with differentiated thyroid cancer cases were retrospectively analyzed data obtained are used SPSS17. 0 statistical software for statistical analysis, mainly using chi-square tests to compare two sets of data X2 to P <0.05 as statistically significant difference.Results: The patients in this study a total of 231 cases, 44 cases were male, female 187 cases, male: female = 1: 4.25, age 12-75 years, mean age 42 ± 10.5. To find the neck mass accounted for 160 cases the first symptom, 63 cases were asymptomatic. Preoperative thyroid ultrasonography, preoperative ultrasound diagnosis had 162 cases of suspected malignancy, ultrasound accuracy rate of 70.1%, preoperative fine needle aspiration were 186 cases, including 132 cases of suspected malignant, 30 cases of thyroid follicular tips epithelial cells and severe dysplasia, fine-needle aspiration of the accuracy rate of 87%, mainly surgical ipsilateral thyroid gland full cut + isthmus resection + contralateral subtotal resection or total thyroidectomy based, post-operative complications There are hoarseness in 18 cases(7.7%), hypocalcemia 20 cases(8.6%), low sound blunt, drinking cough three cases, one case of incision infection, bleeding within 24 hours cutout portion 5 cases, surgery After the main endocrine suppression therapy, the set of data after the primary tumor recurrence or lymph node metastasis were 24 cases, the recurrence rate was 12.9%, factors that affect prognosis and recurrence of differentiated thyroid cancer are mainly clinical stage, age, lymph node metastasis, the degree of cervical lymph nodes in different partitions and scope, surgical approach, tumor size.Conclusion: Patients with differentiated thyroid cancer is more common in female patients mainly, diagnosis relies on thyroid ultrasound, fine needle aspiration, neck CT, thyroid function testing, intraoperative frozen and pathology results of the examination to confirm the diagnosis, surgery for differentiation the main treatment for thyroid cancer, surgery should be based on specific ways the preoperative examination, the lesion nature of the tumor, lymph node metastasis, tumor size, TNM stage and the specific circumstances of the patient may be, the use of standardized endocrine surgery the degree of suppression therapy and I131 treatment, an accurate assessment of preoperative and intraoperative meticulous, strict aseptic technique can reduce the incidence of postoperative complications, the main factors affecting postoperative recurrence of cancer clinical stage, age, lymph node metastasis, lymph node dissection and scope, surgical approach, tumor size.