Observing The Curative Effect Of Gastric Cancer Resection On Type 2 Diabetes Mellitus

Objective:Through observing the efficacy of different gastric cancer resection for improving the glucose level in patients surffering from gastric cancer complicated with type 2 diabetes mellitus,we discusse the therapeutic mechanism of gastric cancer resection for type 2 diabetes mellitus.This study also observes the influence of clinical effect on patients surffering from gastric cancer complicated with type 2 diabetes mellitus by different surgery way.Methods:The retrospective anlysis was used in 45 cases surffering from gastric cancer complicated with type 2 diabetes mellitus.These cases were diveded into 4 groups by different gastric cancer resection-PG(n=10, Proximal gastrectomy radically with remnant gastric esophageal anastomosis),BI(n=11,Billroth I-type distal gastrectomy radically with gastroduodental anastomasis),B II(n=9, Billroth II-type distal gastrectomy radically with gastrojejunal anastomasis),RY( n=15, Total gastric resection radically with Roux-en-Y anastomosis).The level of fasting plasma glucose、glycosylated hemoglobin 、 body mass index and antidiabetic drugs were detected before operation and after operation one month,three month,six month in all cases.At the end of follow-up period,the efficacy of different gastric cancer resection for type2 diabetes mellitus was to be evaluated.Result:PG group,2 cases got improment of type 2 diabetes mellitus and 8 cases had nochange. The effective ratio of PG for treating type 2 diabetes mellitus was 20.0%.B I group,2 cases got improment of type 2 diabetes mellitus and 9 cases had no change. The effective ratio of BI for treating type 2 diabetes mellitus was 18.2%.B II group,2 cases got clinical cure of type 2 diabetes mellitus, 4 cases got improment and 3 cases had no change. The effective ratio of B II for treating type 2diabetes mellitus was 66.7%.RY group,4 cases got clinical cure of type 2 diabetes mellitus, 8 cases got improment and 3 cases had no change. The effective ratio of RY for treating type 2diabetes mellitus was 80.0%.The efficacy had statistical difference btween groups RY and PG(P<0.05),as well as groups RY and BI、BII and PG、BII and BI.However,the efficacy did not have statistical difference between groups PG and BI,as well as groups BII and RY.Conclusion:1.Different gastric cancer resection has different efficacy on type 2 diabetes mellitus.RY and B II can effectively relieve the glucose level in patients suffering from gastric cancer complicated with type 2 diabetes mellitus.The efficacy of RY and BII were better than PG and BI.However,there was no different efficacy btween RY and BII.2.The exclusion of duodenum and forepart jejunum has an importent role for RY and BII.