The Experimental Study Of A Type Of Antireflux Ureteral Stent

Objective :To observe the drainage effects, the role of anti reflux and influence on the urinary function after the new antireflux ureteral stent’s implantation. To explore the feasibility of a new anti-reflux stent. Method :Divided the 4 experimental beagle dogs into J and Y these two groups. The dogs in J group experienced incision of bilateral ureter along with a new and traditional anti-reflux stent were placed in the left and right ureter. The dogs in Y group were placed with a new anti-reflux stent in the left ureteral and a traditional stent in the right through a transvesical retrograde way. Reclassify them into A and B group.Group A(experimental group) stands for ureter which were planted with new anti-reflux stent,a total of four dogs; Group B(Control group) stands for ureter which were planted with traditional anti-reflux stent, also a total of four dogs. After 2 weeks, we observe retrograde problems by using of retrograde cystography. After four weeks the animals were executed and the kidneys ureter were removed. Check if there exist urine leakage around ureter. At the same time, measure the diameter of the ureter in the liquid infusion to know about the ureteral dilatation, and also the pathological changes. Observe the histological change of both kidneys and ureter to know about if there exist reflux, renal pelvis and ureter infection. Result :We do retrograde cystography after 2 weeks which shows gradual increased pressure in the bladder. Traditional ureteral stent placement side have varying degrees of urine reflux, while the new one side was not found any reflux phenomenon. Observe vivo samples after four weeks : In J group, three ureter incision healed well, only one with a small amount leak. The not healed part is the one which placed with traditional ureteral stent. Group Y did not show any difference in the bilateral ureter. These 4 dogs showed no significant expansion of the upper ureter and renal pelvis, the renal volume is normal. Pathological examination showed that compared with traditional ureteral stents side, the new anti-reflux stent placement side turns into severe inflammation. Conclusion : The new ureteral stent have anti-reflux effect. To reduce the upper urinary tract infections, anterograde and retrograde implantation both have good drainage but not lead to urinary tract obstruction. They can better adapt to the current surgical methods which with a certain value.