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Risk Factors Related To Clinical Cases Of Hypertensive Intracerebral Hemorrhage Analysis

Posted on:2016-07-26Degree:MasterType:Thesis
Country:ChinaCandidate:W ChangFull Text:PDF
GTID:2284330476954200Subject:Surgery
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Objective To get out and analyze the related risk factors of HICH(hypertensive in tracerebral hemorrhage), by collecting the hospital for treatment of HICH clinical data, in order to provide a new basis for the prevention and clinical treatment of HICH.Methods The case group was composed by 120 cases of hypertensive intracerebra l hemorrhage, and the control group was composed by 120 cases of hypertension but no intracerebral hemorrhage, in the ratio of 1:1, to conduct self-administered q uestionnaire with the two case groups. The investigation involve(gender, age, med ical history, smoking, alcohol consumption, exercise, work, antihypertensive drug u se, the time of onset, body mass index), biochemical tests(total cholesterol, trigly cerides, low-density lipoprotein, apolipoprotein B, and homocysteine) and head ma gnetic resonance(susceptibility weighted imaging, conventional T1/T2) and other t ests.Result 1 There was no significant difference in terms of gender and age distribu tion of the two groups of patients(P>0.05); 2 The place of hypertensive intracereb ral hemorrhage were mainly on basal ganglia,73 cases(61%); thalamus 30 cases(25%), 11 cases of the cerebellum(9%), brainstem hemorrhage in 6 cases(5%);3 T he proportion of patients in the case group of male than female patients, there wa s a significant difference(P<0.05), in contrast,there was no significant difference in the proportion of male and feale patients in the control group(P>0.05); 4 Hyperte nsive intracerebral hemorrhage patients most vulnerable to disease period 5-7 o’clo ck in the morning(56%); 5 Univariate logistic regression analysis Hint: not the la w of antihypertensive drugs, obesity, smoking, alcohol consumption, diabetes, heart disease, apolipoprotein B, triglycerides, low-density lipoprotein and homocysteine is elevated and cerebral microbleeds risk factors for hypertensive intracerebral hem orrhage, however, physical exercise is a protective factor; 6 Multivariate logistic a nalysis showed: cerebral microbleeds, apolipoprotein B, not the law of oral antihy pertensive drugs for hypertension risk factors in patients with cerebral hemorrhage, on the other side, physical exercise is a protective factor.Conclusions 1 Hypertensive intracerebral bleeding site in the basal ganglia and t halamic hemorrhage the most common. 2 Men, obesity, diabetes and coronary hea rt disease, hyperlipidemia, smoking, alcohol abuse, elevated homocysteine may be risk factors for hypertensive intracerebral hemorrhage, futher, not regular use of an tihypertensive drugs, apolipoprotein B and a history of cerebral microbleeds are th e main risk factors for hypertensive intracerebral hemorrhage; in contrast, physical exercises are protective factors.
Keywords/Search Tags:HICH, Cerebral microbleeds, Susceptibility Weighted Imaging, apolipop rotein B, homocysteine
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