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Brain Blood-oxygen Detection Based On Near-infrared Spectroscopy

Posted on:2015-04-11Degree:MasterType:Thesis
Country:ChinaCandidate:W T XuFull Text:PDF
GTID:2284330473953348Subject:Biomedical engineering
Abstract/Summary:PDF Full Text Request
Neurovascular coupling mechanisms in functional brain activity has always been important areas of brain science. Functional near-infrared spectroscopy(FNIRS) has been utilized in the recent decades for examining functional brain activity by measuring the changes in the concentrations of oxygenated and deoxygenated hemoglobin. As a new tool for detecting of human brain activations, FNIRS can provide excellent temporal sensitivity as well as reasonable spatial sensitivity compared to other functional imaging methods. In particular, the instrumentation which is completely non-invasive can be made portable, unobtrusive, low-cost and low-power. Compared to mature functional near infrared spectroscopy detection technology from abroad, domestic research and development is relatively backward, so far there is no products of functional near-infrared imaging device. This article is the use of near infrared spectroscopy in the study of design and development of systems that detect changes in blood oxygen in brain functional activity.First of all, the paper illustrates the principle of FNIRS, and summarizes the characteristic of FNIRS introduced by near-infrared spectroscopy study on cerebral function in physiological basis at the same time, signal characteristics and application of functional near-infrared imaging technology advantages are summarized.Then, this article highlights based on near infrared spectroscopy technique for cerebral oxygen detection system design and development,including the light emission and transmission hardware design, the use of effective photoelectric sensor for optical signal detection and channel between parallel data acquisition. Also includes software design of each function in the application process. In the process of designing, we also conducted experiments on the validity of the system.The actual data signals attest to the good performance of the system. In addition, this paper presents a method of wavelet analysis for activated channel detection in near-infrared task experiment.Finally, the paper discusses some of the system’s development process optimization and improvement, and discusses the significance of the FNIRS used in conjunction with EEG synchronization.
Keywords/Search Tags:FNIRS, Detection of cerebral blood oxygen, Light source modulation, Optical detection
PDF Full Text Request
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